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Septic Complications and Prognosis After Surgery for Rectal Cancer

  • Original Contribution
  • Published:
Diseases of the Colon & Rectum

Abstract

PURPOSE: The influence of septic complications on long-term prognosis after surgery for rectal cancer is controversial. This study was performed to investigate whether an abdominal or perineal septic complication was associated with rectal cancer recurrence. METHODS: A total of 228 patients who had undergone curative resection for rectal cancer from 1973 to 1992 were reviewed. The patients were divided into groups of those who developed either an intra-abdominal abscess or a perineal infection after surgery (infection group) and those who did not (noninfection group). RESULTS: There was no clear difference in the overall incidence of tumor recurrence between the infection group (19/53, 36 percent) and the noninfection group (46/175, 26 percent; P = 0.25). However, the incidence of local recurrence was higher in the infection group (12/53, 23 percent) than in the noninfection group (16/175, 9 percent; P = 0.02). This increased risk was restricted to patients with a perineal infection (10/30, 33 percent; P = 0.003 vs. the noninfection group), whereas patients with an abdominal infection (3/24, 13 percent) did not differ from the noninfection group. CONCLUSION: Patients with a perineal infection after an abdominoperineal resection have an increased incidence of local recurrence. However, there was no association between abdominal sepsis and prognosis after surgery for rectal cancer.

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References

  1. PH Japui OF Dent R Fischer et al. (1985) ArticleTitleA multivariate analysis of clinical and pathological variables in prognosis of the resection of large bowel cancer. Br J Surg 72 698–702

    Google Scholar 

  2. RK Phillips R Hittinger L Blesowsky JS Fry LP Fielding (1984) ArticleTitleLarge bowel cancer: Br J Surg 71 604–610

    Google Scholar 

  3. JG Docherty JR McGregor M Akyol et al. (1995) ArticleTitleComparison of manually constructed and stapled anastomoses in colorectal surgery. Ann Surg 221 176–184

    Google Scholar 

  4. S Fujita T Teramoto M Watanabe S Kodaira M Kitajima (1993) ArticleTitleAnastomotic leakage after colorectal cancer surgery: Jpn J Clin Oncol 23 229–302

    Google Scholar 

  5. PP Varty EP Laihan PD Golus (1994) ArticleTitleIntra-abdominal sepsis and survival after surgery for colorectal cancer. Br J Surg 81 915–918

    Google Scholar 

  6. C Fuchini L Bandettini M D’Elia F Filipponi A Herd-Smith (1985) ArticleTitleAre postoperative fever and/or septic complications prognostic factors in colorectal cancer resected for cure? Dis Colon Rectum 28 94–95

    Google Scholar 

  7. L Påhlman B Glimelius (1984) ArticleTitleLocal recurrences after surgical treatment for rectal carcinoma. Acta Chir Scand 150 331–335

    Google Scholar 

  8. L Påhlman B Glimelius (1990) ArticleTitlePre- and postoperative radiotherapy in rectal and rectosigmoid carcinoma: Ann Surg 211 187–195

    Google Scholar 

  9. . Swedish Rectal Cancer Trial (1996) ArticleTitleLocal recurrence rate in a randomised multicentre trial of preoperative radiotherapy compared with operation alone in resectable rectal carcinoma. Eur J Surg 162 397–402

    Google Scholar 

  10. G Frykholm B Glimelius L Påhlman (1989) ArticleTitlePreoperative irradiation with and without chemotherapy (MFL) in the treatment of primarily non-resectable adenocarcinoma of the rectum: Eur J Cancer Clin Oncol 25 1535–1541

    Google Scholar 

  11. CD Knight FD Griffin (1980) ArticleTitleImproved technique for low anterior resection of the rectum using the EEA stapler. Surgery 88 810–814

    Google Scholar 

  12. JK McFarlane RD Ryall RJ Heald (1993) ArticleTitleMesorectal excision for rectal cancer. Lancet 341 457–460

    Google Scholar 

  13. B Glimelius L Pahlman (1999) ArticleTitlePreoperative radiotherapy in rectal cancer. Acta Oncol 38 23–32

    Google Scholar 

  14. LL Gunderson (1999) ArticleTitleIndications for and results of combined modality treatment of colorectal cancer. Acta Oncol 38 7–21

    Google Scholar 

  15. . Swedish Rectal Cancer Trial (1993) ArticleTitleInitial report from a Swedish multicenter study examining the role of preoperative irradiation in the treatment of patients with resectable rectal carcinoma. Br J Surg 80 1333–1336

    Google Scholar 

  16. HF Dvorak (1986) ArticleTitleTumors: N Engl J Med 315 1650–1659

    Google Scholar 

  17. L Påhlman P Enblad E Ståhle (1987) ArticleTitleAbdominal vs perineal drainage in rectal surgery. Dis Colon Rectum 30 372–375

    Google Scholar 

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Authors and Affiliations

  1. Departments of Surgery and Oncology, University Hospital, University of Uppsala, Uppsala, Sweden

    Ulf Kressner M.D., Ph.D., Wilhelm Graf M.D., Ph.D., Haile Mahteme M.D., Ph.D., Lars Påhlman M.D., Ph.D. & Bengt Glimelius M.D., Ph.D.

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  1. Ulf Kressner M.D., Ph.D.
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  2. Wilhelm Graf M.D., Ph.D.
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  3. Haile Mahteme M.D., Ph.D.
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  4. Lars Påhlman M.D., Ph.D.
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  5. Bengt Glimelius M.D., Ph.D.
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Kressner, U., Graf, W., Mahteme, H. et al. Septic Complications and Prognosis After Surgery for Rectal Cancer. Dis Colon Rectum 45, 316–321 (2002). https://doi.org/10.1007/s10350-004-6174-4

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  • DOI: https://doi.org/10.1007/s10350-004-6174-4

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