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Regression of Rectal Mucosa-Associated Lymphoid Tissue Lymphoma but Persistence of Helicobacter pylori Infection of Gastric Mucosa After Administration of Levofloxacin: Report of a Case

  • Case Reports
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Diseases of the Colon & Rectum

PURPOSE:

Several articles have reported regression of rectal lymphoma of mucosa-associated lymphoid tissue after anti–Helicobacter pylori therapy. It remains unclear, however, whether lymphoma of rectal mucosa-associated lymphoid tissue is related to Helicobacter pylori infection.

METHODS:

A 60-year-old woman visited our hospital with a complaint of hematochezia. On colonoscopy a pale, ulcerated protrusion approximately 3.5 cm in diameter was found in the rectum. Pathologic diagnosis of a biopsy specimen was low-grade mucosa-associated lymphoid tissue lymphoma. The patient received a ten-day course of levofloxacin, and the cycle was repeated three times over seven months.

RESULTS:

Although persistence of Helicobacter pylori infection was confirmed, the tumor regressed completely.

CONCLUSION:

Our findings in this case suggest that rectal lymphoma of mucosa-associated lymphoid tissue may be related to unknown microorganisms other than Helicobacter pylori. Levofloxacin may be effective for treatment of rectal lymphoma of mucosa-associated lymphoid tissue regardless of Helicobacter pylori infection.

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Authors and Affiliations

  1. Department of Surgery, Fukui Prefectural Hospital, Fukui, Japan

    Kenji Dohden M.D., Osamu Hosokawa M.D., Hiroyuki Hayashi M.D. & Masakazu Hattori M.D.

  2. Department of Pathology, Fukui Prefectural Hospital, Fukui, Japan

    Yasuharu Kaizaki M.D.

Authors
  1. Kenji Dohden M.D.
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  2. Yasuharu Kaizaki M.D.
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  3. Osamu Hosokawa M.D.
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  4. Hiroyuki Hayashi M.D.
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  5. Masakazu Hattori M.D.
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Corresponding author

Correspondence to Kenji Dohden M.D..

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Dohden, K., Kaizaki, Y., Hosokawa, O. et al. Regression of Rectal Mucosa-Associated Lymphoid Tissue Lymphoma but Persistence of Helicobacter pylori Infection of Gastric Mucosa After Administration of Levofloxacin: Report of a Case. Dis Colon Rectum 47, 1544–1546 (2004). https://doi.org/10.1007/s10350-004-0575-2

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  • DOI: https://doi.org/10.1007/s10350-004-0575-2

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