Abstract
A new extraction technique, ionic liquid-assisted extraction (ILAE), has been developed. The ILAE process was further optimized by varying different parameters such as pretreatment time and temperature, ionic liquid/sample ratio, particle size and solvents. Under the optimum conditions, the extraction yield of ILAE was higher than that of Soxhlet extraction. The results of bioassay test showed that crude extract of ILAE was almost the same with that of Soxhlet extraction. The results in this study can serve as a reference for the ILAE of effective constituents in medicinal plants.
References
Sun Y, Liu Z, Wang J, Tian W, Zhou H, Zhu L, Zhang C (2008) Sep Purif Technol 64:221–226. doi:10.1016/j.seppur.2008.10.007
Lau CH, Chan CM, Chan YW, Lau KM, Lau TW, Lam FC, Law WT, Che CT, Leung PC, Fung KP, Ho YY, Lau CBS (2007) Phytomedicine 14:778–784. doi:10.1016/j.phymed.2007.01.007
Doble M, Karthikeyan S, Padmaswar P, Akamanchi K (2005) Biorg Med Chem 13:5996–6001. doi:10.1016/j.bmc.2005.07.027
Ha SH, Mai NL, An G, Koo Y-M (2010) Bioresour Technol. Corrected Proof. doi:10.1016/j.biortech.2010.07.108
Du FY, Xiao XH, Luo XJ, Li GK (2009) Talanta 78:1177–1184. doi:10.1016/j.talanta.2009.01.040
Cao X, Ye X, Lu Y, Yu Y, Mo W (2009) Anal Chim Acta 640:47–51. doi:10.1016/j.aca.2009.03.029
Barthel S, Heinze T (2006) Green Chem 8:301–306. doi:10.1039/b513139a
Zavrel M, Bross D, Funke M, Büchs J, Spiess AC (2009) Bioresour Technol 100:2580–2587. doi:10.1016/j.biortech.2008.11.052
Sun GP, Wan X, Xu SP, Wang H, Liu SH, Wang ZG (2008) Dis Esophagus 21:723–729. doi:10.1111/j.1442-2050.2008.00840.x
Sescousse R, Le KA, Ries ME, Budtova T (2010) J Phys Chem B 114:7222–7228. doi:10.1021/jp1024203
Swatloski R, Spear S, Holbrey J, Rogers R (2002) J Am Chem Soc 124:4974–4975. doi:10.1021/ja025790m
Gericke M, Schlufter K, Liebert T, Heinze T, Budtova T (2009) Biomacromolecules 10:1188–1194. doi:10.1021/bm801430x
Reddy RG, Zhang ZJ, Arenas MF, Blake DM (2003) Thermal stability and corrosivity evaluations of ionic liquids as thermal energy storage media. Freund, Tel Aviv
Marsh KN, Boxall JA, Lichtenthaler R (2004) Fluid Phase Equilib 219:93–98. doi:10.1016/j.fluid.2004.02.003
Wagner I, Stichlmair J (2001) Chem Eng Technol 24:616–619. doi:10.1002/1521-4125(200106)24:6<616:aid-ceat616>3.0.co;2-t
Liu W, Cheng L, Zhang Y, Wang H, Yu M (2008) J Mol Liq 140:68–72. doi:10.1016/j.molliq.2008.01.008
Heinze T, Schwikal K, Barthel S (2005) Macromol Biosci 5:520–525. doi:10.1002/mabi.200500039
Du F, Xiao X, Li G (2007) J Chromatogr A 1140:56–62. doi:10.1016/j.chroma.2006.11.049
Yu Y, Chen B, Chen Y, Xie M, Duan H, Li Y, Duan G (2009) J Sep Sci 32:4227–4233. doi:10.1002/jssc.200900487
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Jin, R., Fan, L. & An, X. Ionic Liquid-Assisted Extraction of Paeonol from Cynanchum paniculatum . Chromatographia 73, 787–792 (2011). https://doi.org/10.1007/s10337-010-1865-6
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10337-010-1865-6