Skip to main content
Log in

Ionic Liquid-Assisted Extraction of Paeonol from Cynanchum paniculatum

  • Full Short Communication
  • Published:
Chromatographia Aims and scope Submit manuscript

Abstract

A new extraction technique, ionic liquid-assisted extraction (ILAE), has been developed. The ILAE process was further optimized by varying different parameters such as pretreatment time and temperature, ionic liquid/sample ratio, particle size and solvents. Under the optimum conditions, the extraction yield of ILAE was higher than that of Soxhlet extraction. The results of bioassay test showed that crude extract of ILAE was almost the same with that of Soxhlet extraction. The results in this study can serve as a reference for the ILAE of effective constituents in medicinal plants.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

References

  1. Sun Y, Liu Z, Wang J, Tian W, Zhou H, Zhu L, Zhang C (2008) Sep Purif Technol 64:221–226. doi:10.1016/j.seppur.2008.10.007

    Article  CAS  Google Scholar 

  2. Lau CH, Chan CM, Chan YW, Lau KM, Lau TW, Lam FC, Law WT, Che CT, Leung PC, Fung KP, Ho YY, Lau CBS (2007) Phytomedicine 14:778–784. doi:10.1016/j.phymed.2007.01.007

    Article  CAS  Google Scholar 

  3. Doble M, Karthikeyan S, Padmaswar P, Akamanchi K (2005) Biorg Med Chem 13:5996–6001. doi:10.1016/j.bmc.2005.07.027

    Article  CAS  Google Scholar 

  4. Ha SH, Mai NL, An G, Koo Y-M (2010) Bioresour Technol. Corrected Proof. doi:10.1016/j.biortech.2010.07.108

  5. Du FY, Xiao XH, Luo XJ, Li GK (2009) Talanta 78:1177–1184. doi:10.1016/j.talanta.2009.01.040

    Article  CAS  Google Scholar 

  6. Cao X, Ye X, Lu Y, Yu Y, Mo W (2009) Anal Chim Acta 640:47–51. doi:10.1016/j.aca.2009.03.029

    Article  CAS  Google Scholar 

  7. Barthel S, Heinze T (2006) Green Chem 8:301–306. doi:10.1039/b513139a

    Article  CAS  Google Scholar 

  8. Zavrel M, Bross D, Funke M, Büchs J, Spiess AC (2009) Bioresour Technol 100:2580–2587. doi:10.1016/j.biortech.2008.11.052

    Article  CAS  Google Scholar 

  9. Sun GP, Wan X, Xu SP, Wang H, Liu SH, Wang ZG (2008) Dis Esophagus 21:723–729. doi:10.1111/j.1442-2050.2008.00840.x

    Article  Google Scholar 

  10. Sescousse R, Le KA, Ries ME, Budtova T (2010) J Phys Chem B 114:7222–7228. doi:10.1021/jp1024203

    Article  CAS  Google Scholar 

  11. Swatloski R, Spear S, Holbrey J, Rogers R (2002) J Am Chem Soc 124:4974–4975. doi:10.1021/ja025790m

    Article  CAS  Google Scholar 

  12. Gericke M, Schlufter K, Liebert T, Heinze T, Budtova T (2009) Biomacromolecules 10:1188–1194. doi:10.1021/bm801430x

    Article  CAS  Google Scholar 

  13. Reddy RG, Zhang ZJ, Arenas MF, Blake DM (2003) Thermal stability and corrosivity evaluations of ionic liquids as thermal energy storage media. Freund, Tel Aviv

  14. Marsh KN, Boxall JA, Lichtenthaler R (2004) Fluid Phase Equilib 219:93–98. doi:10.1016/j.fluid.2004.02.003

    Article  CAS  Google Scholar 

  15. Wagner I, Stichlmair J (2001) Chem Eng Technol 24:616–619. doi:10.1002/1521-4125(200106)24:6<616:aid-ceat616>3.0.co;2-t

    Article  CAS  Google Scholar 

  16. Liu W, Cheng L, Zhang Y, Wang H, Yu M (2008) J Mol Liq 140:68–72. doi:10.1016/j.molliq.2008.01.008

    Article  CAS  Google Scholar 

  17. Heinze T, Schwikal K, Barthel S (2005) Macromol Biosci 5:520–525. doi:10.1002/mabi.200500039

    Article  CAS  Google Scholar 

  18. Du F, Xiao X, Li G (2007) J Chromatogr A 1140:56–62. doi:10.1016/j.chroma.2006.11.049

    Article  CAS  Google Scholar 

  19. Yu Y, Chen B, Chen Y, Xie M, Duan H, Li Y, Duan G (2009) J Sep Sci 32:4227–4233. doi:10.1002/jssc.200900487

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xiaoning An.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jin, R., Fan, L. & An, X. Ionic Liquid-Assisted Extraction of Paeonol from Cynanchum paniculatum . Chromatographia 73, 787–792 (2011). https://doi.org/10.1007/s10337-010-1865-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10337-010-1865-6

Keywords

Navigation