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Two-dimensional XD-GRASP provides better image quality than conventional 2D cardiac cine MRI for patients who cannot suspend respiration

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Abstract

Objectives

Residual respiratory motion degrades image quality in conventional cardiac cine MRI (CCMRI). We evaluated whether a free-breathing (FB) radial imaging CCMRI sequence with compressed sensing reconstruction [extradimensional (e.g. cardiac and respiratory phases) golden-angle radial sparse parallel, or XD-GRASP] could provide better image quality than a conventional Cartesian breath-held (BH) sequence in an unselected population of patients undergoing clinical CCMRI.

Materials and methods

One hundred one patients who underwent BH and FB imaging in a midventricular short-axis plane at a matching location were included. Visual and quantitative image analysis was performed by two blinded experienced readers, using a five-point qualitative scale to score overall image quality and visual signal-to-noise ratio (SNR) grade, with measures of noise and sharpness. End-diastolic and end-systolic left ventricular areas were also measured and compared for both BH and FB images.

Results

Image quality was generally better with the BH cines (overall quality grade for BH vs FB images 4 vs 2.9, p < 0.001; noise 0.06 vs 0.08 p < 0.001; SNR grade 4.1 vs 3, p < 0.001), except for sharpness (p = 0.48). There were no significant differences between BH and FB images regarding end-diastolic or end-systolic areas (p = 0.35 and p = 0.12). Eighteen of the 101 patients had poor BH image quality (grade 1 or 2). In this subgroup, the quality of the FB images was better (p = 0.0032), as was the SNR grade (p = 0.003), but there were no significant differences regarding noise and sharpness (p = 0.45 and p = 0.47).

Conclusion

Although FB XD-GRASP CCMRI was visually inferior to conventional BH CCMRI in general, it provided improved image quality in the subgroup of patients with respiratory-motion-induced artifacts on BH images.

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Authors and Affiliations

  1. Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, 660 First Ave., New York, NY, USA

    Eve Piekarski, Teodora Chitiboi, Rebecca Ramb, Li Feng & Leon Axel

  2. Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, 660 First Ave., New York, NY, USA

    Eve Piekarski, Teodora Chitiboi, Rebecca Ramb, Li Feng & Leon Axel

  3. Department of Radiology, New York University Langone Medical Center, 650 First Ave., New York, NY, USA

    Larry A. Latson Jr, Puneet Bhatla & Leon Axel

Authors
  1. Eve Piekarski
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  2. Teodora Chitiboi
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  3. Rebecca Ramb
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  4. Larry A. Latson Jr
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  5. Puneet Bhatla
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  6. Li Feng
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  7. Leon Axel
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Contributions

EP participated in the data collection and the data analysis and wrote the manuscript. TC participated in the data collection and the data analysis and reviewed the manuscript. RR participated in the data analysis and reviewed the manuscript. LAL participated in the data collection and reviewed the manuscript. PB participated in the data collection and reviewed the manuscript. LF participated in the protocol development and reviewed the manuscript. LA designed the project development, participated in the data analysis, and redacted and reviewed the manuscript.

Corresponding author

Correspondence to Leon Axel.

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Funding

This study was funded by the NIH (Grant Number NIH R21-EB109595-01).

Conflict of interest

The authors declare that they have no competing interests.

Research involving human participants and informed consent

This retrospective study was approved by our institutional review board and was performed according to standards of the Health Insurance Portability and Accountability Act. Documentation of consent was waived.

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Piekarski, E., Chitiboi, T., Ramb, R. et al. Two-dimensional XD-GRASP provides better image quality than conventional 2D cardiac cine MRI for patients who cannot suspend respiration. Magn Reson Mater Phy 31, 49–59 (2018). https://doi.org/10.1007/s10334-017-0655-7

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  • DOI: https://doi.org/10.1007/s10334-017-0655-7

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