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Effects of air susceptibility on proton resonance frequency MR thermometry

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Abstract

Object

The temperature dependence of the proton resonance frequency (PRF) is often used in MR thermometry. However, this method is prone to even very small changes in local magnetic field strength. Here, we report on the effects of susceptibility changes of surrounding air on the magnetic field inside an object and their inferred effect on the measured MR temperature.

Materials and methods

MR phase thermometry was performed on spherical agar phantoms enclosed in cylindrical containers at 7 T. The air susceptibility inside the cylindrical container was changed by both heating the air and changing the gas composition.

Results

Changing the temperature of surrounding air from 23 to 69°C caused an apparent MR temperature error of 2 K. When ambient air was displaced by 100% oxygen, the MR temperature error increased to 40 K. The magnetic field shift and therefore error in inferred MR temperature scales linearly with volume susceptibility change and has a strong and nontrivial dependence on the experimental configuration.

Conclusion

Air susceptibility changes associated with oxygen concentration changes greatly affect PRF MR thermometry measurements. Air temperature changes can also affect these measurements, but to a smaller degree. For uncalibrated MR thermometry, air susceptibility changes may be a significant source of error.

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Authors and Affiliations

  1. Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstr. 1a, 04103, Leipzig, Germany

    Markus N. Streicher, Andreas Schäfer, Enrico Reimer, Bibek Dhital, Robert Trampel, Dimo Ivanov & Robert Turner

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  1. Markus N. Streicher
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  2. Andreas Schäfer
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  3. Enrico Reimer
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  4. Bibek Dhital
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  5. Robert Trampel
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  6. Dimo Ivanov
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  7. Robert Turner
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Correspondence to Markus N. Streicher.

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Streicher, M.N., Schäfer, A., Reimer, E. et al. Effects of air susceptibility on proton resonance frequency MR thermometry. Magn Reson Mater Phy 25, 41–47 (2012). https://doi.org/10.1007/s10334-011-0249-8

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  • DOI: https://doi.org/10.1007/s10334-011-0249-8

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