Abstract
Objective
There is controversy about the best therapeutic surgical approach for treatment of patients with T4 gastric cancer. We evaluated the survival benefit of resection in this group of patients.
Methods
We retrospectively reviewed the hospital records of 288 patients with T4 gastric carcinoma to compare the clinicopathological results in patients with curative resection (n = 49) with patients with non-curative resection (n = 113) from 1980 to 2000.
Results
Curative resection was performed in 49 (30.2%) patients, with the pancreas being the most frequently resected organ. The 5-year survival rate was 9.3% and the median survival time was 12 months for all 162 registered patients. The 5-year survival rates in patients after curative and non-curative resection were 14.3% vs 7.1% respectively. These values differed considerably between the two groups (P = 0.033). Operative type and curability were independent statistically significant prognostic parameters.
Conclusion
Curability was an independent prognostic factor among all registered patients. Patients with T4 gastric carcinoma might be benefited from curative resection.
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Lin, D., Lu, P., Liu, C. et al. Surgical outcomes in patients with T4 gastric carcinoma: a retrospective study of 162 patients. Chin. -Ger. J. Clin. Oncol. 8, 599–602 (2009). https://doi.org/10.1007/s10330-009-0121-8
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DOI: https://doi.org/10.1007/s10330-009-0121-8