Abstract
There is a growing interest for aromatic and biological properties of essential oils as alternatives to synthetic chemicals and drugs. However, essential oils and their components are poorly soluble in aqueous systems and are highly sensitive to degradation and evaporation. These drawbacks can be overcome by encapsulation into cyclodextrins, which are non-toxic cyclic oligosaccharides obtained from the enzymatic degradation of starch. Cyclodextrins inclusion complexes offer solutions to many limitations of the use of essential oils in the food, pharmaceutical and cosmetic industries. This article reviews essential oils encapsulation in cyclodextrins. The strength of binding between cyclodextrins and essential oils components covers a wide range of formation constants with values ranging from 13 to 166,338 M−1. The encapsulation in cyclodextrins can increase the aqueous solubility of essential oils up to 16-fold and reduce their photodegradation rates up to 44-fold, while ensuring a gradual release. We also discuss the effect of encapsulation on biological activities, such as antimicrobial and antioxidant properties of essential oils. Finally, we present novel cyclodextrin-based approaches in the sectors of textiles and nanofibres.
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(Adapted from Dima and Dima 2015)
Reprinted with permission from Kfoury et al. (2016g)
Reprinted with permission from Kfoury et al. 2015b
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Notes
FDA: Code Fed. Regul. (CFR). Title 21 Food Drugs. Chapter I—Food Drug Adm. Dep. Heal. Hum. Serv. Subchapter B—Food Hum. Consum. (Continued), Part 182–Subst. Gen. Recognized as Safe (GRAS). 2016.
Essential Oil Market Analysis By Product (Orange, Corn Mint, Eucalyptus, Citronella, Peppermint, Lemon, Clove Leaf, Lime, Spearmint), By Application (Medical, Food & Beverage, Spa & Relaxation, Cleaning & Home) And Segment Forecasts To 2024.
See Vraz Kresevic et al. (2008).
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Authors thank Marc Fourmentin from the University of the Littoral Opal Coast (ULCO), France, for the illustrations.
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Kfoury, M., Auezova, L., Greige-Gerges, H. et al. Encapsulation in cyclodextrins to widen the applications of essential oils. Environ Chem Lett 17, 129–143 (2019). https://doi.org/10.1007/s10311-018-0783-y
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DOI: https://doi.org/10.1007/s10311-018-0783-y