Résumé
Cinq extraits flavonoiques obtenus des feuilles de Marrubium vulgare L. ont ete testes sur quatre souches bacteriennes (Pseudomonas aeruginosa ATCC 27835, Escherichia coli ATCC 25922, Bacillus cereus ATCC 1306 et Staphylococcus aureus ATCC 13565) et deux souches fongiques (Penicillium digitatum ATCC 201167 et Aspergillus niger ATCC 16404). Ils presentent un remarquable effet antibacterien sur les bacteries Gram+ et une activite antifongique moderee. Les concentrations minimales inhibitrices (CMI) varient entre 6,25 et 50 μg/ml en fonction de l’extrait flavonoique et de la souche microbienne. Le screening phytochimique et la chromatographie sur couche mince (CCM) ont revele l’existence de certaines classes flavonoiques qui pourraient etre responsables du pouvoir antimicrobien de Marrubium vulgare L.
Abstract
Five flavonoic extracts obtained from the leaves of Marrubium vulgare L. were tested on four bacterial strains (Pseudomonas aeruginosa ATCC 27835, Escherichia coli ATCC 25922, Bacillus cereus ATCC 1306 and Staphylococcus aureus ATCC 13565) and two fungal strains (Penicillium digitatum ATCC 201167 and Aspergillus niger ATCC 16404). They present a remarkable antibacterial effect on the Gram+ bacteria and a moderate antifungal activity. The minimal inhibitory concentrations (MICs) vary between 6.25 and 50 μg/ml according to the flavonoic extract and microbial strain. The phytochemical screening and the thin layer chromatography (TLC) showed the existence of some classes of flavonoids being able to be responsible for the antimicrobial power of Marrubium vulgare L.
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Bouterfas, K., Mehdadi, Z., Latreche, A. et al. Pouvoir antimicrobien des flavonoïdes extraits des feuilles de Marrubium vulgare L. en provenance du mont de Tessala (Algérie occidentale). Phytothérapie 12, 6–14 (2014). https://doi.org/10.1007/s10298-014-0830-6
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DOI: https://doi.org/10.1007/s10298-014-0830-6