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Restoration of autonomic cardiovascular regulation in spinal cord injury with epidural stimulation: a case series

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Acknowledgements

We are indebted to our research participants for their courage and perseverance that made these findings possible. We are grateful to Christie Ferreira, Richard Seither, Brittany Logsdon, Katelyn Smith, and Sean Stills for their participant support; Dr. Camilo Castillo, Dr. Darryl Kaelin, Dr. Glenn Hirsch, Courtney Ware, Yukishia Austin, Lynn Robbins, and Hye Conner for medical oversight; Dengzhi Wang and Hanna Martin for data analysis.

Funding

This study was supported by the Craig H. Neilsen Foundation, The Leona M. and Harry B. Helmsley Charitable Trust, University of Louisville Hospital, Christopher and Dana Reeve Foundation, and Medtronic plc.

Author information

Authors and Affiliations

  1. Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, KY, USA

    Bonnie E. Legg Ditterline, Sevda C. Aslan, Siqi Wang, Beatrice Ugiliweneza & Susan Harkema

  2. Department of Neurosurgery, University of Louisville, Louisville, KY, USA

    Bonnie E. Legg Ditterline, Sevda C. Aslan, Siqi Wang, Beatrice Ugiliweneza & Susan Harkema

  3. Division of Cardiology, Department of Medicine, National Jewish Health, Denver, CO, USA

    Glenn A. Hirsch

  4. Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY, USA

    Glenn A. Hirsch

  5. James J. Peters VA Medical Center, Bronx, NY, USA

    Jill M. Wecht

  6. VA RR&D Service Center for the Medical Consequences of Spinal Cord Injury, Bronx, NY, USA

    Jill M. Wecht

  7. Departments of Medicine and Rehabilitation Medicine, Icahn School of Medicine, New York, NY, USA

    Jill M. Wecht

  8. Frazier Rehabilitation Institute, 220 Abraham Flexner Way, Louisville, KY, 40202, USA

    Susan Harkema

Authors
  1. Bonnie E. Legg Ditterline
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  2. Sevda C. Aslan
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  3. Siqi Wang
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  4. Beatrice Ugiliweneza
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  5. Glenn A. Hirsch
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  6. Jill M. Wecht
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  7. Susan Harkema
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Contributions

BLD, SA, JMW, and SJH drafted and edited the manuscript; BLD, and SW acquired the data; SW and SA created programs to analyze the data; BLD, SA, and SW analyzed the data; BU created the statistical models; all co-authors interpreted the results, contributed intellectually, and critically revised the manuscript.

Corresponding author

Correspondence to Susan Harkema.

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Conflict of interest

B.L.D, S.A., S.W., B.U., G.A.H, J.M.W, and S.J.H. declare no competing financial interests exist.

Data sharing

Deidentified data and study-related documents will be made available upon reasonable request.

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Legg Ditterline, B.E., Aslan, S.C., Wang, S. et al. Restoration of autonomic cardiovascular regulation in spinal cord injury with epidural stimulation: a case series. Clin Auton Res 31, 317–320 (2021). https://doi.org/10.1007/s10286-020-00693-2

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  • DOI: https://doi.org/10.1007/s10286-020-00693-2

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