Résumé
En 20 ans, le taux de contrôle local des sarcomes des tissus mous est passé d’environ 70 à 80 %, grâce entre autres aux progrès de la chirurgie. En dehors des centres spécialisés, la prise en charge des sarcomes reste encore insuffisante, en particulier au moment initial. Ce papier détaille les pièges à éviter au moment du diagnostic, comment procéder à la biopsie. La chirurgie d’exérèse est une chirurgie réglée, dont la place doit être discutée dans un cadre de prise en charge pluridisciplinaire. Une exérèse intempestive peut compromettre les chances de guérison. Elle est évaluée selon le système de la maladie résiduelle (R), qui aide à mieux adapter le traitement complémentaire.
Abstract
Surgical advances over the last twenty years have increased the rate of local control of soft tissue sarcoma from 70 to 80 %. However, the management of soft tissue sarcoma, especially initial treatment, remains inadequate outside specialized treatment centres. This paper discusses how to minimize diagnostic errors and perform biopsies. Soft tissue sarcoma surgery requires careful planning and must be integrated into a multidisciplinary therapeutic approach. A “whoops” excision can compromise a patient’s prognosis. The quality of surgery is best evaluated by the UICC residual disease (R) system, which helps to adapt complementary treatments.
Références
Bauer H, Trovik C, Alvegard T, et al. (2001) Monitoring referral and treatment in soft tissue sarcoma. Study based on 1,851 patients from the Scandinavian Sarcoma Group register. Acta Orthop Scand 72: 150–159
Bonvalot S, Laplanche A, Lejeune F, et al. (2005) Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-alpha be better? Ann Oncol 16: 1061–1068
Coindre JM, Terrier P, Bui NB, et al. (1996) Prognostic factors in adult patients with locally controlled soft tissue sarcoma. A study on 546 patients from the French Federation of Cancer Centers sarcoma group. J Clin Oncol 14: 869–877
Engellau J, Bendahl PO, Persson A, et al. (2005) Improved prognostication in soft tissue sarcoma: independent information from vascular invasion, necrosis, growth pattern, and immunostaining using whole-tumor sections and tissue micro-arrays. Hum Pathol 36: 994–1002
Fédération nationale des centres de lutte contre le cancer (1995) Standards, options et recommandations. Sarcomes des tissus mous et ostéosarcomes. Vol 1, 1st ed. Paris: Arnette Blackwell 6–113
Gerrand CH, Wunder JS, Kandel RA, et al. (2001) Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence. J Bone Joint Surg 83: 1149–1115
Ghnassia JP, Vilain MO, Coindre JM, et al. (1998) Recommendations pour la prise en charge anatomopathologique des sarcomes des tissus mous de l’adulte. Ann Pathol 18: 505–511
Hau A, Kim I, Kattapuram S, Hornicek FJ, et al. (2002) Accuracy of CT-guided biopsies in 359 patients with musculos-keletal lesions. Skeletal Radiol 31: 349–353
Hoeber I, Spillane AJ, Fisher C, et al. (2001) Accuracy of biopsy techniques for limb and limb girdle soft tissue tumors. Ann Surg Oncol 8(1): 80–87
Lawrence W, Donegan WL, Nachimuth N, et al. (1987) Adult soft tissue sarcoma. A pattern of care of the American college of Surgeons. Ann Surg 205: 349–359
Llacer C, Delannes M, Minsat M, et al. (2006) Low-dose intraoperative brachytherapy in soft tissue sarcomas involving neurovascular structure. Radiother Oncol 2006; 78: 10–16
Mankin HJ, Lange TA, Spanier SS (1982) The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. J Bone Joint Surg 64A: 1121–1127
Mankin HJ, Lange TA, Spanier SS (2006) The classic: the hazards of biopsy in patients with malgnant primary bone and soft-tissue tumors. Clin Orthop Rel Res 450: 4–10
Ray-Coquard I, Ranchère-Vince D, Thiesse P, et al (2003) Evaluation of core needle biopsy as a substitute to open biopsy in the diagnosis of soft-tissue masses. Eur J Cancer 39: 2021–2025
Ray-Coquard I, Thiesse P, Ranchère-Vince D, et al. (2004) Conformity to clinical practice guidelines, multidisciplinary management and outcome of treatment for soft tissue sarcomas. Ann Oncol 15: 307–315
Sastre-Garau X, Coindre JM, Leroyer A, et al. (1997) Predictive factors for complete removal in soft tissue sarcomas: a retrospective analysis in a series of 592 cases. J Surg Oncol 65: 175–182
Stoeckle E, Rivoire M (1996) Chirurgie des sarcomes des tissus mous (rétropéritoine excepté). Ann Chir 50: 263–275
Stoeckle E (1997) Nouvelles techniques chirurgicales des sarcomes des tissus mous. Cancer Radiother 1: 453–456
Stoeckle E (2006) Chirurgie des sarcomes des tissus mous des membres et de la paroi du tronc. Cancer Radiother 10: 34–40
Stoeckle E, Gardet H, Coindre JM, et al. (2006) Prospective evaluation of quality of surgery in soft tissue sarcoma. Eur J Surg Oncol 1–7
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Stöckle, E., Coindre, J.M., Thomas, L. et al. Chirurgie des sarcomes des tissus mous des membres et de la paroi du tronc. Oncologie 9, 107–113 (2007). https://doi.org/10.1007/s10269-006-0556-2
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DOI: https://doi.org/10.1007/s10269-006-0556-2