Abstract.
The anti-tumor activity of the immune system in the setting of hematopoietic stem cell transplantation has largely been described in the context of the “graft-versus-tumor” effect of allogeneic stem cell transplantation. This article reviews clinical evidence suggesting the existence of an autologous graft-versus-tumor effect in the setting of host immune system recovery following autologous stem cell transplantation resulting in prolongation of survival of cancer patients.
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Porrata, L.F., Markovic, S.N. Timely reconstitution of immune competence affects clinical outcome following autologous stem cell transplantation. Clin Exp Med 4, 78–85 (2004). https://doi.org/10.1007/s10238-004-0041-4
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DOI: https://doi.org/10.1007/s10238-004-0041-4