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Infant brain subjected to oscillatory loading: material differentiation, properties, and interface conditions

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Biomechanics and Modeling in Mechanobiology Aims and scope Submit manuscript

Abstract

Past research into brain injury biomechanics has focussed on short duration impulsive events as opposed to the oscillatory loadings associated with Shaken Baby Syndrome (SBS). A series of 2D finite element models of an axial slice of the infant head were created to provide qualitative information on the behaviour of the brain during shaking. The test series explored variations in subarachnoid cerebrospinal fluid (CSF) representation, brain matter stiffness, dissipation, and nonlinearity, and differentiation of brain matter type. A new method of CSF modelling based on Reynolds lubrication theory was included to provide a more realistic brain–CSF interaction. The results indicate that solid CSF representation for this load regime misrepresents the phase lag of displacement, and that the volume of subarachnoid CSF, and inclusion of thickness variations due to gyri, are important to the resultant behavior. Stress concentrations in the deep brain are reduced by fluid redistribution and gyral contact, while inclusion of the pia mater significantly reduces cortex contact strains. These results provide direction for future modelling of SBS.

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Abbreviations

SBS:

Shaken baby syndrome

CSF:

Cerebrospinal fluid

FSI:

Fluid–structure interaction

FE:

Finite element

MRI:

Magnetic resonance imaging

QLV:

Quasilinear viscoelastic

CNS:

Central nervous system

ALE:

Arbitrary lagrange euler

SPH:

Smooth particle hydrodynamics

PFEM:

Particle finite element method

CFD:

Computational fluid dynamics

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Authors and Affiliations

  1. School of Engineering, University of Queensland, Brisbane, 4072, Australia

    Zac Couper & Faris Albermani

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  1. Zac Couper
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  2. Faris Albermani
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Correspondence to Faris Albermani.

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Couper, Z., Albermani, F. Infant brain subjected to oscillatory loading: material differentiation, properties, and interface conditions. Biomech Model Mechanobiol 7, 105–125 (2008). https://doi.org/10.1007/s10237-007-0079-9

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  • DOI: https://doi.org/10.1007/s10237-007-0079-9

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