Abstract
We report a case of fibroblastic rheumatism (FR) in a 61-year-old woman. The patient showed sclerodactyly and polyarthritis that involved both her hands and feet joints. Levels of C-reactive protein and matrix metallopeptidase-3 were within normal range. We diagnosed her condition as FR according to both the clinical features characterized with the destructive change of multiple joints and the histological sample. This is the first FR published case of FR in an Asian individual, and 23 published cases were reviewed.
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References
Chaouat Y, Aron-Brnetiere R, Faures B, Bient O, Ginet C, Aubart D. Une nouvelle entite: le rheumatisme fibloblastique. Rev Rhum Mal Osteoartic. 1980;47:345–51.
Lévigne V, Perrot JL, Faisant M, Deville V, Claudy AL. Rhumatisme fibroblastque. Ann Dermatol Venereol. 1990;117:199–202.
Fam AG, Hanna W, Mak V, Assaad D. Fibroblastic rheumatism: clinical and histologic evolution of cutaneous manifestations. J Rheumatol. 1998;25:2261–6.
Chkirate B, Job-Deslandre C. Rhumatisme fibroblastique: a propos dun cas. Arch Pediatr. 2001;8:389–92.
Lee JM, Sundel RP, Liang MG. Fibroblastic rheumatism: case report and review of the literature. Pediatr Dermatol. 2002;19:532–5.
Colonna L, Barbieri C, Di Lella G, et al. Fibroblastic rheumatism: a case report. Acta Derm Venereol. 2002;82:200–3.
Pedersen JK, Poulsen T, Hørslev-Petersen K. Fibroblastic rheumatism: a Scandinavian case report. Ann Rheum Dis. 2005;64:156–7.
Réty F, Tayebjee OA, Servettaz A, Godmer P, Le Van An JC, Laredo JD, et al. Radiological bone lesions in fibroblastic rheumatism; case report. Presse Med. 2007;36:432–6.
Kluger N, Dumas-Tesici A, Hamel D, Brousse N, Fraitag S. Fibroblastic rheumatism: fibromatosis rather than non-Langerhans cell histiocytosis. J Cutan Pathol. 2009 (Epub ahead of print).
O’Dell JR. Rheumatoid arthritis: the clinical picture. In: Koopman WJ, Moreland LW, editors. Arthritis and allied conditions. 15th ed. Philadelphia: Lippincott William & Wilkins; 2005. p. 1165–90.
Bennett RM. Psoriatic arthritis. In: Koopman WJ, Moreland LW, editors. Arthritis and allied conditions. 15th ed. Philadelphia: Lippincott William & Wilkins; 2005. p. 1357–71.
Silver RM, Medsger Jr TA, Bolster MB. Systemic sclerosis and scleroderma variants: clinical aspects. In: Koopman WJ, Moreland LW, editor. Arthritis and allied conditions. 15th ed. Philadelphia: Lippincott William & Wilkins; 2005. p. 1633–68.
Champbell DA, Edwards NL. Multicentric reticulohistiocytosis: systemic macrophage disorder. Baillieres Clin Rheumatol. 1991;5:301–9.
Zelger B, Burgdorf W. Fibroblastic rheumatism: a variant of non-Langerhans cell histiocytoses? Pediatr Dermatol. 2003;20:461–2.
Vittecoq O, Mejjad O, da Silva F, Joly P, Thomine E, Lauret P, et al. Preliminary experience with low-dose methotrexate in fibroblastic rheumatism. Arthritis Rheum. 1996;39:2070–3.
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Watanabe, S., Kamada, K., Imai, H. et al. An Asian case of fibroblastic rheumatism: clinical, radiological, and histological features. Mod Rheumatol 20, 423–426 (2010). https://doi.org/10.1007/s10165-010-0297-3
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DOI: https://doi.org/10.1007/s10165-010-0297-3