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A pediatric patient with neuro-Behçet’s disease

  • CASE REPORT
  • Published:
Modern Rheumatology

Abstract

Behçet’s disease is rare in childhood. We describe a 10-year-old boy with neuro-Behçet’s disease (NB) who presented with fever, headache, vertigo, and hearing loss. An examination of the cerebrospinal fluid (CSF) revealed pleocytosis as well as elevated protein and interleukin (IL)-6 levels. Brain magnetic resonance imaging (MRI) showed hyperintensity of the right thalamus and midbrain on T2-WI, and gadolinium (Gd) enhancement of left acoustic nerve origin. HLA-B51 was positive. Prednisolone combined with methotrexate resulted in a complete remission. Brain MRI and the CSF IL-6 level were useful for the diagnosis and monitoring of this pediatric patient with NB.

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Author notes

  1. Saori Hatachi

    Present address: Department of Medicine, Division of Clinical Immunology and Rheumatology, Kitano Hospital, Osaka, Japan

  2. Gohichi Kageyama

    Present address: Division of Rheumatology, Kurashiki Central Hospital, Kurashiki, Japan

  3. Masahiro Koshiba

    Present address: Department of Clinical Laboratory Medicine, Hyogo College of Medicine, Nishinomiya, Japan

Authors and Affiliations

  1. Department of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan

    Saori Hatachi, Takashi Nakazawa, Akio Morinobu, Shinpei Kasagi, Yoshinori Kogata, Gohichi Kageyama, Seiji Kawano, Masahiro Koshiba & Shunichi Kumagai

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  1. Saori Hatachi
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  2. Takashi Nakazawa
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  3. Akio Morinobu
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  4. Shinpei Kasagi
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  9. Shunichi Kumagai
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Corresponding author

Correspondence to Shunichi Kumagai.

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Hatachi, S., Nakazawa, T., Morinobu, A. et al. A pediatric patient with neuro-Behçet’s disease. Mod Rheumatol 16, 321–323 (2006). https://doi.org/10.1007/s10165-006-0507-1

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  • DOI: https://doi.org/10.1007/s10165-006-0507-1

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