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Reversible posterior leukoencephalopathy syndrome after blood transfusion in a patient with end-stage renal disease

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Abstract

A 42-year-old female end-stage renal disease (ESRD) patient with reversible posterior leukoencephalopathy syndrome (RPLS) post-transfusion during initiation of hemodialysis is reported. Eleven days after the onset of illness, we diagnosed encephalopathy as a grand mal seizure resulting from diffuse cerebral edema. One reason for the delayed diagnosis was that her symptom, a throbbing headache that occurred during her first dialysis, indicated dialysis disequilibrium syndrome. We must bear in mind that a small amount of transfusion could cause RPLS even during the first dialysis. To our knowledge, this is the first case report on RPLS after blood transfusion in an ESRD patient.

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The authors have declared that no conflict of interest exists.

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Authors and Affiliations

  1. Division of Nephrology, Department of Internal Medicine, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aoba-ku, Yokohama, Japan

    Yoshinori Sato, Makoto Hirose, Yoshihiko Inoue, Daisuke Komukai, Mamiko Takayasu, Eri Kawashima, Fumihiko Koiwa & Ashio Yoshimura

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  1. Yoshinori Sato
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  2. Makoto Hirose
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  3. Yoshihiko Inoue
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  4. Daisuke Komukai
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  5. Mamiko Takayasu
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  6. Eri Kawashima
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  7. Fumihiko Koiwa
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  8. Ashio Yoshimura
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Correspondence to Yoshinori Sato.

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Sato, Y., Hirose, M., Inoue, Y. et al. Reversible posterior leukoencephalopathy syndrome after blood transfusion in a patient with end-stage renal disease. Clin Exp Nephrol 15, 942–947 (2011). https://doi.org/10.1007/s10157-011-0515-0

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  • DOI: https://doi.org/10.1007/s10157-011-0515-0

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