Abstract
We studied the clinical utility of the detection of lipoarabinomannan antibody, using MycoDot, in pleural fluid for the diagnosis of tuberculous pleurisy. Nine patients with active tuberculous pleurisy, 1 patient with chronic tuberculous empyema, and 16 patients with nontuberculous pleural effusions were studied. The results were positive in 5 patients with tuberculous pleural disease. Sensitivity was 50% (5 of 10; including the 1 patient with chronic tuberculous empyema) and specificity was 93.8% (15 of 16). Detection of lipoarabinomannan antibody using MycoDot in pleural fluid is a specific diagnostic tool for tuberculous pleurisy; furthermore, this diagnostic method is simple, rapid, and cost-effective.
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Yokoyama, T., Rikimaru, T., Kinoshita, T. et al. Clinical utility of lipoarabinomannan antibody in pleural fluid for the diagnosis of tuberculous pleurisy. J Infect Chemother 11, 81–83 (2005). https://doi.org/10.1007/s10156-004-0366-7
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DOI: https://doi.org/10.1007/s10156-004-0366-7