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Factors predicting incisional surgical site infection in patients undergoing open radical cystectomy for bladder cancer

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Abstract

Background

The risk factors of incisional surgical site infection (iSSI) after open radical cystectomy (ORC) have not been fully investigated. The aim of the present study is to examine factors correlated with iSSI development after ORC with intestinal urinary diversion.

Methods

A total of 178 patients who had undergone ORC with intestinal urinary diversion between 2003 and 2012 at our institution were included in this retrospective study. Correlations between different perioperative factors and iSSI development were determined using univariate and multivariate logistic regression analyses.

Results

iSSI was observed in 53 patients (29.8 %). In the univariate analysis, age, diabetes mellitus, thickness of subcutaneous fat (TSF), and allogeneic transfusion were significant predictors of iSSI development. Although subcutaneous closed-suction drainage (SCSD) was not a significant factor in univariate analysis, SCSD, age, and TSF were all finally identified as independent predictors of iSSI development (P = 0.020, P < 0.001, and P = 0.022, respectively). Further analyses demonstrated that SCSD was frequently used in patients with relatively thick subcutaneous fat tissue and that SCSD significantly decreased iSSI development in these patients.

Conclusions

Advanced patient age, thick subcutaneous fat tissue, and the absence of SCSD were significantly associated with iSSI development in bladder cancer patients who underwent ORC with intestinal urinary diversion. SCSD may be a useful procedure for iSSI prevention, especially in patients with relatively thick subcutaneous fat tissue.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan

    Tatsuo Gondo, Yoshio Ohno, Jun Nakashima, Takeshi Hashimoto, Issei Takizawa, Ayako Tanaka, Kenji Shimodaira, Naoya Satake, Hisashi Takeuchi, Yoshihiro Nakagami, Makoto Ohori & Masaaki Tachibana

Authors
  1. Tatsuo Gondo
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  2. Yoshio Ohno
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  3. Jun Nakashima
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  4. Takeshi Hashimoto
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  5. Issei Takizawa
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  6. Ayako Tanaka
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  7. Kenji Shimodaira
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  8. Naoya Satake
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  9. Hisashi Takeuchi
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  10. Yoshihiro Nakagami
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  11. Makoto Ohori
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  12. Masaaki Tachibana
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Corresponding author

Correspondence to Yoshio Ohno.

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Gondo, T., Ohno, Y., Nakashima, J. et al. Factors predicting incisional surgical site infection in patients undergoing open radical cystectomy for bladder cancer. Int J Clin Oncol 19, 935–939 (2014). https://doi.org/10.1007/s10147-013-0646-2

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  • DOI: https://doi.org/10.1007/s10147-013-0646-2

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