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Primary retroperitoneal mucinous cystadenocarcinoma with mural nodules: a case report and literature review

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Abstract

A primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is an extremely rare lesion. To date, only 49 cases have been reported. The presence of mural nodules in a PRMC may indicate a worse prognosis. We report the case of a 40-year-old Japanese woman with a PRMC with mural nodules. Microscopic examination revealed that the stromal cells of the nodules were spindle-shaped and varied in size. The nodules were immunoreactive for vimentin but negative for cytokeratin and EMA, and the nuclei of the stromal cells were pleomorphic and strongly Ki-67 immunoreactive. The nodules were diagnosed as true sarcoma. To the best of our knowledge, this is 11th published case report of a PRMC with mural nodules.

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Conflict of interest

The authors declare that there is no conflict of interest.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Tomoko Kanayama, Kiyoshi Yoshino, Takayuki Enomoto, Masami Fujita, Yutaka Ueda, Toshihiro Kimura, Eiji Kobayashi & Tadashi Kimura

  2. Department of Pathology, Graduate School of Medicine, Osaka University, Suita, Japan

    Hiroshi Ohashi & Eiichi Morii

Authors
  1. Tomoko Kanayama
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  2. Kiyoshi Yoshino
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  3. Takayuki Enomoto
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  4. Hiroshi Ohashi
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  5. Masami Fujita
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  6. Yutaka Ueda
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  7. Toshihiro Kimura
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  8. Eiji Kobayashi
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  9. Eiichi Morii
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  10. Tadashi Kimura
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Corresponding author

Correspondence to Kiyoshi Yoshino.

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Kanayama, T., Yoshino, K., Enomoto, T. et al. Primary retroperitoneal mucinous cystadenocarcinoma with mural nodules: a case report and literature review. Int J Clin Oncol 17, 407–411 (2012). https://doi.org/10.1007/s10147-011-0313-4

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  • DOI: https://doi.org/10.1007/s10147-011-0313-4

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