Abstract
This review discusses the usefulness of bedside lung ultrasound in the diagnostic distinction between different causes of acute dyspnea in the emergency setting, particularly focusing on differential diagnosis of pulmonary edema and exacerbation of chronic obstructive pulmonary disease (COPD). This is possible using a simple unit and easy-to-acquire technique performed by radiologists and clinicians. Major advantages include bedside availability, absence of radiation, high feasibility and reproducibility, and cost efficiency. The technique is based on analysis of sonographic artifacts instead of direct visualization of pulmonary structures. Artifacts are because of interactions between water-rich structures and air and are called “comet tails” or B lines. When such artifacts are widely detected on anterolateral transthoracic lung scans, we diagnose diffuse alveolar-interstitial syndrome, which is often a sign of acute pulmonary edema. This condition rules out exacerbation of COPD as the main cause of an acute dyspnea.
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Lichtenstein D, Mezière G, Biderman P, Gepner A, Barré O (1997) The comet tail artifact. An ultrasound sign of alveolar-interstitial syndrome. Am J Respir Crit Care Med 156:1640–1646
Holleman DR, Simel DL (1995) Does the clinical examination predict airflow limitation. JAMA 273:313–319
Badgett RG, Lucey CR, Mulrow CD (1997) Can the clinical examination diagnose left-sided heart failure in adults. JAMA 277:1712–1719
Mulrow CD, Lucey CR, Farnett LE (1993) Discriminating causes of dyspnea through clinical examination. J Gen Intern Med 8:383–392
Schmitt BP, Kushner MS, Wiener SL (1986) The diagnostic usefulness of the history of the patient with dyspnea. J Gen Intern Med 1:386–393
Stevenson LW, Perloff JK (1989) The limited reliability of physical signs for estimating hemodynamics in chronic heart failure. JAMA 261:884–888
Milne EN, Pistolesi M, Miniati M, Giuntini C (1985) The radiologic distinction of cardiogenic and noncardiogenic edema. AJR Am J Roentgenol 144:879–894
Collins SP, Lindsell CJ, Storrow AB, Abraham WT, ADHERE Scientific Advisory CommitteeInvestigators and Study Group (2006) Prevalence of negative chest radiography results in the emergency department patient with decompensated heart failure. Ann Emerg Med 47:13–18
Davis M, Espiner E, Richards G, Billings J, Town I, Neill A, Drennan C, Richards M, Turner J, Yandle T (1994) Plasma brain natriuretic peptide in assessment of acute dyspnoea. Lancet 343:440–444
Dao Q, Krishnaswamy P, Kazanegra R, Harrison A, Amirnovin R, Lenert L, Clopton P, Alberto J, Hlavin P, Maisel AS (2001) Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent-care setting. J Am Coll Cardiol 37:379–385
Morrison LK, Harrison A, Krishnaswamy P, Kazanegra R, Clopton P, Maisel A (2002) Utility of a rapid B-natriuretic peptide assay in differentiating congestive heart failure from lung disease in patients presenting with dyspnea. J Am Coll Cardiol 39:202–209
Collins SP, Ronan-Bentle S, Storrow AB (2003) Diagnostic and prognostic usefulness of natriuretic peptides in emergency department patients with dyspnea. Ann Emerg Med 41:532–545
Davie AP, Love MP, McMurray JJ (1996) Value of ECGs in identifying heart failure due to left ventricular systolic dysfunction. BMJ 313:300–301
Lien CT, Gillespie ND, Struthers AD, McMurdo ME (2002) Heart failure in frail elderly patients: diagnostic difficulties, co-morbidities, polypharmacy and treatment dilemmas. Eur J Heart Fail 4:91–98
Ray P, Birolleau S, Lefort Y, Becquemin MH, Beigelman C, Isnard R, Teixeira A, Arthaud M, Riou B, Boddaert J (2006) Acute respiratory failure in the elderly: etiology, emergency diagnosis and prognosis. Crit Care 10:R82
Lichtenstein DA (2007) Ultrasound in the management of thoracic disease. Crit Care Med 35:S250–S261
Reissig A, Kroegel C (2003) Transthoracic sonography of diffuse parenchymal lung disease: the role of comet tail artifacts. J Ultrasound Med 22:173–180
Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M, Picano E (2004) Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Card 93:1265–1270
Volpicelli G, Mussa A, Garofalo G, Cardinale L, Casoli G, Perotto F, Fava C, Frascisco M (2006) Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome. Am J Emerg Med 24:689–696
Soldati G, Testa A, Silva FR, Carbone L, Portale G, Silveri NG (2006) Chest ultrasonography in lung contusion. Chest 130:533–538
Lichtenstein D, Mezière G, Biderman P, Gepner A (1999) The comet-tail artifact: an ultrasound sign ruling out pneumothorax. Intensive Care Med 25:383–388
Lichtenstein DA, Mezière G, Lascols N, Biderman P, Courret JP, Gepner A, Goldstein I, Tenoudji-Cohen M (2005) Ultrasound diagnosis of occult pneumothorax. Crit Care Med 33:1231–1238
Volpicelli G, Caramello V, Cardinale L, Mussa A, Bar F, Frascisco MF (2008) Detection of sonographic B lines in patients with normal lungs or radiographic alveolar consolidation. Med Sci Monit (in press)
Agricola E, Bove T, Oppizzi M, Marino G, Zangrillo A, Margonato A et al (2005) Ultrasound comet-tail images: a marker of pulmonary edema: a comparative study with wedge pressure and extravascular lung water. Chest 127:1690–1695
Wohlgenannt S, Gehmacher O, Gehmacher U, Kopf A, Mathis G (2001) Sonographic findings in interstitial lung diseases. Ultraschall Med 22:27–31
Lichtenstein D, Mezière G (1998) A lung ultrasound sign allowing bedside distinction between pulmonary edema and COPD: the comet tail artifact. Intensive Care Med 24:1331–1334
Lichtenstein D, Mezière G (2003) Ultrasound diagnosis of an acute dyspnea [abstract]. Critical Care 777(suppl 2):P189
Volpicelli G, Caramello V, Cardinale L, Mussa A, Bar F, Frascisco M (2008) Bedside ultrasound of the lung for the monitoring of acute decompensated heart failure. Am J Em Med accepted (in press)
Fagenholz PJ, Gutman JA, Murray AF, Noble VE, Thomas SH, Harris NS (2007) Chest ultrasonography for the diagnosis and monitoring of high-altitude pulmonary edema. Chest 131:1013–1018
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Volpicelli, G., Cardinale, L., Garofalo, G. et al. Usefulness of lung ultrasound in the bedside distinction between pulmonary edema and exacerbation of COPD. Emerg Radiol 15, 145–151 (2008). https://doi.org/10.1007/s10140-008-0701-x
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DOI: https://doi.org/10.1007/s10140-008-0701-x