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Efficacy of ILIB on periodontal clinical parameters and glycemic control in patients with periodontitis and type II diabetes—randomized clinical trial

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Abstract

Our study aimed to study the efficacy of ILIB on periodontal parameters and glycemic control in patients with periodontitis and type II diabetes. Twenty-one patients in a randomized clinical trial were divided into 2 groups: control group (CG), conventional periodontal therapy, and test group (TG), conventional periodontal treatment associated with 10 laser applications by the ILIB-Modified (ILIB-M) technique. Fasting blood glucose levels and glycated hemoglobin (HbA1c), visible plaque index (VPI), gingival bleeding index (GBI), and periodontal clinical parameters were evaluated at baseline and after 4 months (T4). Regarding periodontal parameters, the intragroup analysis showed a statistically significant reduction (p < 0.05) between baseline and T4, for the VPI, GBI, BOP, PD, and CAL indexes. However, in the intergroup analysis, no statistically significant improvements (p > 0.05) were observed between the TG and CG for the VPI, GBI, BOP, PD, and CAL indexes. Regarding HbA1C and fasting blood glucose values, no statistically significant improvements were observed in intergroup and intragroup analyses (p > 0.05). The Modified ILIB did not improve the periodontal clinical parameters and glycemic control in patients with type II diabetes.

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Acknowledgements

The authors would like to thank the support of UFRN for allowing this study to be possible, and the Coordination for the improvement of Higher Education Personnel (CAPES) for their support during the preparation of this article.

Funding

The authors received funding from the Coordination of Improvement of Higher Education Person (CAPES).

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Authors and Affiliations

  1. Dentistry Department, Rio Grande Do Norte Federal University, Av. Senador Salgado Filho, 1787, Lagoa Nova, Natal, RN, CEP 59056-000, Brazil

    Francisco Leonardo da Silva Júnior, Davi Neto de Araújo Silva, Marcela Letícia da Silva Azevedo, Natália Teixeira da Silva, Hursula Cardoso Almeida, Regia Carla Medeiros da Silva, Kenio Costa de Lima, Éricka Janine Dantas da Silveira & Ana Rafaela Luz de Aquino Martins

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  1. Francisco Leonardo da Silva Júnior
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  2. Davi Neto de Araújo Silva
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  3. Marcela Letícia da Silva Azevedo
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  4. Natália Teixeira da Silva
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  5. Hursula Cardoso Almeida
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  6. Regia Carla Medeiros da Silva
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  8. Éricka Janine Dantas da Silveira
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  9. Ana Rafaela Luz de Aquino Martins
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The authors have no relevant financial or non-financial interests to disclose.

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Correspondence to Ana Rafaela Luz de Aquino Martins.

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Ethics approval

This study was submitted to the Research Ethics Committee and approved under the protocol number 2,932,923, and was conducted in accordance with the Helsinki Declaration of 1975, as revised in 2013.

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da Silva Júnior, F.L., de Araújo Silva, D.N., da Silva Azevedo, M.L. et al. Efficacy of ILIB on periodontal clinical parameters and glycemic control in patients with periodontitis and type II diabetes—randomized clinical trial. Lasers Med Sci 37, 1945–1952 (2022). https://doi.org/10.1007/s10103-021-03455-2

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  • DOI: https://doi.org/10.1007/s10103-021-03455-2

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