Skip to main content

Advertisement

Log in

Green Light photoselective vaporization of the prostate: a safe and effective treatment for elderly high-risk benign prostate hyperplasia patients with gland over 80 ml

  • Original Article
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript

Abstract

To analyze the efficacy of Green Light photoselective vaporization of the prostate (PVP) in elderly high-risk benign prostatic hyperplasia (BPH) patients with glands over 80 ml. From December 2013 to February 2016, we allocated 84 elderly (age 71–97) high-risk patients who underwent preoperative transrectal ultrasound (TRUS) examination with glands over 80 ml and divided them into two groups to receive 120 W (n = 40) and 180 W (n = 44) PVP. All the patients have been observed at least one intraoperative comorbidity: hypertension, diabetes mellitus, NYHA II, or combined. They were followed up for 12 months. All the conventional parameters were compared in this study. All the patients received successful operations without severe complications, and no patient needed blood transfusion. The operation time and catheterization time of the 180 W patients were significantly shorter than that of the 120 W patients (p < 0.05). The International Prostate Symptom Scores (IPSS), quality of life (QoL) scores, maximum flow rate (Qmax), and residual urine volume (RUV) in both groups have been significantly improved. PVP is safe and effective for high-risk aging patients with gland over 80 ml. In addition, 180 W XPS system has a short operation time and catheterization time and less inflammatory response.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Irwin DE, Milsom I, Hunskaar S, Reilly K, Kopp Z, Herschorn S, Coyne K, Kelleher C, Hampel C, Artibani W, Abrams P (2006) Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol 50(6):1306–1314; discussion 1314-1305. https://doi.org/10.1016/j.eururo.2006.09.019

    Article  Google Scholar 

  2. Kim EH, Larson JA, Andriole GL (2016) Management of benign prostatic hyperplasia. Annu Rev Med 67:137–151. https://doi.org/10.1146/annurev-med-063014-123902

    Article  CAS  PubMed  Google Scholar 

  3. Lepor H, Kazzazi A, Djavan B (2012) Alpha-blockers for benign prostatic hyperplasia: the new era. Curr Opin Urol 22(1):7–15. https://doi.org/10.1097/MOU.0b013e32834d9bfd

    Article  PubMed  Google Scholar 

  4. Yeo JK, Choi H, Bae JH, Kim JH, Yang SO, Oh CY, Cho YS, Kim KW, Kim HJ (2016) Korean clinical practice guideline for benign prostatic hyperplasia. Investig Clin Urol 57(1):30–44. https://doi.org/10.4111/icu.2016.57.1.30

    Article  PubMed  PubMed Central  Google Scholar 

  5. Yu X, Elliott SP, Wilt TJ, McBean AM (2008) Practice patterns in benign prostatic hyperplasia surgical therapy: the dramatic increase in minimally invasive technologies. J Urol 180(1):241–245; discussion 245. https://doi.org/10.1016/j.juro.2008.03.039

    Article  PubMed  Google Scholar 

  6. Christidis D, McGrath S, Perera M, Manning T, Bolton D, Lawrentschuk N (2017) Minimally invasive surgical therapies for benign prostatic hypertrophy: the rise in minimally invasive surgical therapies. Prostate Int 5(2):41–46. https://doi.org/10.1016/j.prnil.2017.01.007

    Article  PubMed  PubMed Central  Google Scholar 

  7. Sievert KD, Kunit T (2017) Emerging techniques in ‘truly’ minimal-invasive treatment options of benign prostatic obstruction. Curr Opin Urol 27(3):287–292. https://doi.org/10.1097/MOU.0000000000000386

    Article  PubMed  Google Scholar 

  8. Broggi E, May A, Giretti G, Tabchouri N, Lorphelin H, Brichart N, Bruyere F (2014) Long-term outcomes of 80-watt KTP and 120-watt HPS GreenLight photoselective vaporization of the prostate. Urol Int 93(2):229–236. https://doi.org/10.1159/000356991

    Article  CAS  PubMed  Google Scholar 

  9. Bachmann A, Muir GH, Collins EJ, Choi BB, Tabatabaei S, Reich OM, Gomez-Sancha F, Woo HH (2012) 180-W XPS GreenLight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures. Eur Urol 61(3):600–607. https://doi.org/10.1016/j.eururo.2011.11.041

    Article  PubMed  Google Scholar 

  10. Al-Ansari A, Younes N, Sampige VP, Al-Rumaihi K, Ghafouri A, Gul T, Shokeir AA (2010) GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia: a randomized clinical trial with midterm follow-up. Eur Urol 58(3):349–355. https://doi.org/10.1016/j.eururo.2010.05.026

    Article  PubMed  Google Scholar 

  11. Anderson BB, Pariser JJ, Helfand BT (2015) Comparison of patients undergoing PVP versus TURP for LUTS/BPH. Curr Urol Rep 16(8):55. https://doi.org/10.1007/s11934-015-0525-7

    Article  PubMed  Google Scholar 

  12. Bachmann A, Tubaro A, Barber N, d'Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyere F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitan C, Knispel H, Thomas JA (2014) 180-W XPS GreenLight laser vaporisation versus transurethral resection of the prostate for the treatment of benign prostatic obstruction: 6-month safety and efficacy results of a European Multicentre Randomised Trial—the GOLIATH study. Eur Urol 65(5):931–942. https://doi.org/10.1016/j.eururo.2013.10.040

    Article  PubMed  Google Scholar 

  13. Emara AM, Barber NJ (2014) The continuous evolution of the Greenlight laser; the XPS generator and the MoXy laser fiber, expanding the indications for photoselective vaporization of the prostate. J Endourol 28(1):73–78. https://doi.org/10.1089/end.2013.0356

    Article  PubMed  Google Scholar 

  14. Lee DJ, Rieken M, Halpern J, Zhao F, Pueschel H, Chughtai B, Kaplan SA, Lee RK, Bachmann A, Te AE (2016) Laser vaporization of the prostate with the 180-W XPS-Greenlight laser in patients with ongoing platelet aggregation inhibition and oral anticoagulation. Urology 91:167–173. https://doi.org/10.1016/j.urology.2016.01.021

    Article  PubMed  Google Scholar 

  15. Rieken M, Bachmann A, Shariat SF (2016) Long-term follow-up data more than 5 years after surgical management of benign prostate obstruction: who stands the test of time? Curr Opin Urol 26(1):22–27. https://doi.org/10.1097/MOU.0000000000000244

    Article  PubMed  Google Scholar 

  16. Mavuduru RM, Mandal AK, Singh SK, Acharya N, Agarwal M, Garg S, Kumar S (2009) Comparison of HoLEP and TURP in terms of efficacy in the early postoperative period and perioperative morbidity. Urol Int 82(2):130–135. https://doi.org/10.1159/000200786

    Article  CAS  PubMed  Google Scholar 

  17. Pathak RA, Broderick GA, Igel TC, Petrou SP, Young PR, Wehle MJ, Heckman MG, Diehl NN, Vargas ER, Shah K, Thiel DD (2017) Impact of minimally invasive benign prostatic hyperplasia therapies on 30- and 90-day postoperative office encounters. Urology 99:186–191. https://doi.org/10.1016/j.urology.2016.10.015

    Article  PubMed  Google Scholar 

  18. Berquet G, Corbel L, Della Negra E, Huet R, Trifard F, Codet Y, Bouliere F, Verhoest G, Vincendeau S, Bensalah K, Mathieu R (2015) Prospective evaluation of ambulatory laser vaporization of the prostate for benign prostatic hyperplasia. Lasers Surg Med 47(5):396–402. https://doi.org/10.1002/lsm.22363

    Article  PubMed  Google Scholar 

  19. Bouchier-Hayes DM, Van Appledorn S, Bugeja P, Crowe H, Challacombe B, Costello AJ (2010) A randomized trial of photoselective vaporization of the prostate using the 80-W potassium-titanyl-phosphate laser vs transurethral prostatectomy, with a 1-year follow-up. BJU Int 105(7):964–969. https://doi.org/10.1111/j.1464-410X.2009.08961.x

    Article  PubMed  Google Scholar 

  20. Lukacs B, Loeffler J, Bruyere F, Blanchet P, Gelet A, Coloby P, De la Taille A, Lemaire P, Baron JC, Cornu JN, Aout M, Rousseau H, Vicaut E, Group RS (2012) Photoselective vaporization of the prostate with GreenLight 120-W laser compared with monopolar transurethral resection of the prostate: a multicenter randomized controlled trial. Eur Urol 61(6):1165–1173. https://doi.org/10.1016/j.eururo.2012.01.052

    Article  PubMed  Google Scholar 

  21. Zorn KC, Liberman D (2011) GreenLight 180W XPS photovaporization of the prostate: how I do it. Can J Urol 18(5):5918–5926

    PubMed  Google Scholar 

  22. Eken A, Soyupak B, Acil M, Arpaci T, Akbas T (2015) Safety, efficacy and outcomes of the new GreenLight XPS 180W laser system compared to the GreenLight HPS 120W system for the treatment of benign prostatic hyperplasia in a prospective nonrandomized single-centre study. Can Urol Assoc J 9(1–2):e56–e60. https://doi.org/10.5489/cuaj.2263

    Article  PubMed  PubMed Central  Google Scholar 

  23. Sohn JH, Choi YS, Kim SJ, Cho HJ, Hong SH, Lee JY, Hwang TK, Kim SW (2011) Effectiveness and safety of photoselective vaporization of the prostate with the 120 W HPS Greenlight laser in benign prostatic hyperplasia patients taking oral anticoagulants. Korean J Urol 52(3):178–183. https://doi.org/10.4111/kju.2011.52.3.178

    Article  PubMed  PubMed Central  Google Scholar 

  24. Cakiroglu B, Gozukucuk R, Sinanoglu O (2013) Efficacy and safety of 120 w greenlight photoselective vaporisation of prostate in patients receiving anticoagulant drugs. J Pak Med Assoc 63(12):1464–1467

    PubMed  Google Scholar 

  25. Elterman DS (2015) How I do it: GreenLight XPS 180W photoselective vaporization of the prostate. Can J Urol 22(3):7836–7843

    PubMed  Google Scholar 

  26. Ben-Zvi T, Hueber PA, Liberman D, Valdivieso R, Zorn KC (2013) GreenLight XPS 180W vs HPS 120W laser therapy for benign prostate hyperplasia: a prospective comparative analysis after 200 cases in a single-center study. Urology 81(4):853–858. https://doi.org/10.1016/j.urology.2012.12.031

    Article  PubMed  Google Scholar 

  27. Luo F, Sun HH, Su YH, Zhang ZH, Wang YS, Zhao Z, Li J (2017) GreenLight laser photoselective vaporization of the prostate for treatment of benign prostate hyperplasia/lower urinary tract symptoms in patients with different post-void residual urine. Lasers Med Sci 32(4):895–901. https://doi.org/10.1007/s10103-017-2190-1

    Article  PubMed  Google Scholar 

  28. Hueber PA, Liberman D, Ben-Zvi T, Woo H, Hai MA, Te AE, Chughtai B, Lee R, Rutman M, Gonzalez RR, Barber N, Al-Hathal N, Al-Qaoud T, Trinh QD, Zorn KC (2013) 180 W vs 120 W lithium triborate photoselective vaporization of the prostate for benign prostatic hyperplasia: a global, multicenter comparative analysis of perioperative treatment parameters. Urology 82(5):1108–1113. https://doi.org/10.1016/j.urology.2013.03.059

    Article  PubMed  Google Scholar 

  29. Shigemura K, Fujisawa M (2018) Current status of holmium laser enucleation of the prostate. Int J Urol 25(3):206–211. https://doi.org/10.1111/iju.13507

    Article  PubMed  Google Scholar 

  30. Cho MC, Ha SB, Oh SJ, Kim SW, Paick JS (2015) Change in storage symptoms following laser prostatectomy: comparison between photoselective vaporization of the prostate (PVP) and holmium laser enucleation of the prostate (HoLEP). World J Urol 33(8):1173–1180. https://doi.org/10.1007/s00345-014-1424-0

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

All patients have signed informed consent documents and agreed to receive the treatment. This study has been proved by the Ethics Committee of our hospital.

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sun, J., Shi, A., Tong, Z. et al. Green Light photoselective vaporization of the prostate: a safe and effective treatment for elderly high-risk benign prostate hyperplasia patients with gland over 80 ml. Lasers Med Sci 33, 1693–1698 (2018). https://doi.org/10.1007/s10103-018-2521-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10103-018-2521-x

Keywords

Navigation