Abstract
Glomuvenous malformations are uncommon simple vascular malformations that might be present at birth or appear during childhood that have been classically classified as a subtype of venous malformations. Sclerotherapy and surgery have been used in the past as treatments for this condition although with disappointing results in large glomangiomas. The treatment of these lesions has still not been standardized. We conducted a retrospective study of 17 patients treated with dual wavelength PDL-Nd:YAG. The majority of the patients experience a reduction of at least a 60% in their glomuvenous malformations. Treatment was well-tolerated, and adverse effects were rare.
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References
Boon LM, Mulliken JB, Enjolras O, Vikkula M (2004) Glomuvenous malformation (glomangioma) and venous malformation: distinct clinicopathologic and genetic entities. Arch Dermatol 140:971–976
Brouillard P, Boon LM, Mulliken et al (2002) Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations (“glomangiomas”). Am J Hum Genet 70:866–874
Brouillard P, Ghassibé M, Penington A, Boon LM, Dompmartin A, Temple IK et al (2005) Four common glomulin mutations cause two thirds of glomuvenous malformations (“familial glomangiomas”): evidence for a founder effect. J Med Genet 42:e13
Grillo E, Boixeda P, Paoli J et al (2013) Congenital plaque-like glomangioma treated successfully with dual wavelength pulsed-dye and neodymium:yttrium-aluminum-garnet laser. Photodermatol Photoimmunol Photomed 29(4):212
Trost J, Buckley C, Smidt AC (2015) Long-pulsed neodymium-doped yttrium aluminum garnet laser for glomuvenous malformations in adolescents. Pediatr Dermatol 32:217–218
Phillips CB, Guerrero C, Theos A (2015) Nd:YAG laser offers promising treatment option for familial glomuvenous malformation. Dermatol Online J 16:21(4)
Rivers JK, Rivers CA, Li MK, Martinka M (2016) Laser therapy for an acquired glomuvenous malformation (glomus tumour): a nonsurgical approach. J Cutan Med Surg 20:80–83
Hughes R, Lacour JP, Chiaverini C, Rogopoulos A, Passeron T (2011) Nd:YAG laser treatment for multiple cutaneous glomangiomas: report of 3 cases. Arch Dermatol 147:255–256
Nguyen TV, Becker EM, Miller WA, Browning JC (2014) Plaque-type glomuvenous malformations successfully treated using combined pulsed dye laser and neodymium-doped yttrium aluminum garnet laser. Dermatol Surg 40:89–92
Vargas-Navia N, Baselga E, Muñoz-Garza FZ, Puig L (2017) Congenital plaque-type glomuvenous malformation: 11 years of follow-up and response to treatment with the combined pulsed-dye and neodymium:yttrium-aluminum-garnet laser. Actas Dermosifiliogr 108:72–74
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Moreno-Arrones, O.M., Jimenez, N., Alegre-Sanchez, A. et al. Glomuvenous malformations: dual PDL-Nd:YAG laser approach. Lasers Med Sci 33, 2007–2010 (2018). https://doi.org/10.1007/s10103-018-2493-x
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DOI: https://doi.org/10.1007/s10103-018-2493-x