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Superpulsed laser therapy on healing process after tooth extraction in patients waiting for liver transplantation

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Abstract

Alveolar healing following tooth extraction is a complex repair process involving different tissues, including epithelium and bone. This research aimed to study the effect of laser therapy on alveolar healing process in patients waiting for liver transplantation, evaluating some inflammation, osteogenesis, and clinical parameters. Twelve patients with hepatic failure waiting for liver transplantation, with indications to bilateral extraction, entered the split-mouth study. One post-extractive defect was treated with laser while the other was left without treatment. Specimens of soft tissues were removed from around the tooth before extraction and after 7 days. Superpulsed laser irradiation prevented IL-1β increase and induced IL-6, IL-10, and collagen III increase at 7 days in comparison to their level before extraction, whereas the other parameters were unmodified. Moreover, the epithelial regeneration evidenced a positive result of laser therapy, and the patients reported less pain in the site treated with laser. In conclusion, laser therapy appears to be the treatment of choice for patients due to its clinical efficacy, safety, good tolerance, and its ability to prevent inflammation.

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Acknowledgments

This research work was supported by grants from Regione Piemonte and the University of Turin, Italy.

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Authors and Affiliations

  1. Oral Surgery Unit, Dentistry Section, Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy

    Marco Mozzati, Nadia Cocero & Renato Pol

  2. Department of Experimental Medicine and Oncology, University of Turin, Turin, Italy

    Germana Martinasso, Marina Maggiora, Giuliana Muzio & Rosa Angela Canuto

  3. Dipartimento di Medicina ed Oncologia Sperimentale, Università di Torino, Corso Raffaello 30, 10125, Torino, Italy

    Rosa Angela Canuto

Authors
  1. Marco Mozzati
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  2. Germana Martinasso
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  3. Nadia Cocero
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  4. Renato Pol
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  5. Marina Maggiora
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  6. Giuliana Muzio
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  7. Rosa Angela Canuto
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Correspondence to Rosa Angela Canuto.

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Mozzati, M., Martinasso, G., Cocero, N. et al. Superpulsed laser therapy on healing process after tooth extraction in patients waiting for liver transplantation. Lasers Med Sci 27, 353–359 (2012). https://doi.org/10.1007/s10103-010-0880-z

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  • DOI: https://doi.org/10.1007/s10103-010-0880-z

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