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Influence of laser (660 nm) on functional recovery of the sciatic nerve in rats following crushing lesion

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Abstract

With the aim of accelerating the regenerative processes, the objective was to study the influence of gallium–aluminum–arsenide (GaAlAs) laser (660 nm) on functional and histomorphological recovery of the sciatic nerve in rats. The sciatic nerves of 12 Wistar rats were crushed divided into two groups: control and laser therapy. For the latter, GaAlAs laser was utilized (660 nm, 4 J/cm2, 26.3 mW and 0.63 cm2 beam), at three equidistant points on the lesion, for 20 days. Comparison of the sciatic functional index (SFI) showed that there was a significant difference only between the pre-lesion value of the laser therapy group and that after the 21st day in the control group. It was concluded that the parameters and methods utilized demonstrated positive results regarding the SFI over the time period evaluated.

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Authors and Affiliations

  1. University for State and Pantanal Region Development (UNIDERP), Campo Grande, Mato Grosso do Sul, Brazil

    Ana Carulina Guimarães Belchior, Filipe Abdalla dos Reis, Iandara Schettert Silva, Daniel M. Perreira & Paulo de Tarso Camillo de Carvalho

  2. Research and Development Institute of the University of the Paraíba Valley (UNIVAP), Tissue Biomodulation Laboratory, São José dos Campos, São Paulo, Brazil

    Ana Carulina Guimarães Belchior, Filipe Abdalla dos Reis & Renata Amadei Nicolau

  3. Rua Abricó do Pará, 146, Carandá Bosque, 79032-423, Campo Grande, Mato Grosso do Sul, Brazil

    Paulo de Tarso Camillo de Carvalho

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  1. Ana Carulina Guimarães Belchior
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  2. Filipe Abdalla dos Reis
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  3. Renata Amadei Nicolau
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Correspondence to Paulo de Tarso Camillo de Carvalho.

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Belchior, A.C.G., dos Reis, F.A., Nicolau, R.A. et al. Influence of laser (660 nm) on functional recovery of the sciatic nerve in rats following crushing lesion. Lasers Med Sci 24, 893–899 (2009). https://doi.org/10.1007/s10103-008-0642-3

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  • DOI: https://doi.org/10.1007/s10103-008-0642-3

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