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Effect of different LLLT on pituitrin-induced bradycardia in the rabbit

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Abstract

The objective of this paper was to observe the effect of low-level combined- or single-laser irradiation on bradycardia produced by pituitrin in rabbits. A combined-laser apparatus was made. A 10.6-μm CO2 laser and a 650-nm semiconductor laser, transmitted by different optical fibers, converged to output and irradiate on the Neiguan (PC6) acupuncture point in rabbits with bradycardia produced by pituitrin. Thirty minutes after the model was set, the heart rates of the combined-laser Neiguan group made quicker recoveries than those of the model control group, the laser-control group, or the single-laser Neiguan group (P<0.05), and the heart rates of the single-CO2-laser Neiguan group were similar to those of the normal group (P>0.05). However, there were significant differences between the 650-nm-laser Neiguan group and the normal control group (P<0.05). The combined-laser irradiation certainly has a curative effect on bradycardia produced by pituitrin. A single CO2 laser could accelerate the recovery from bradycardia, while single 650-nm-laser irradiation on the Neiguan acupoint does not produce such an effect.

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Acknowledgements

This project was partially supported by 973 Program of China (2005CB523306), the National Natural Science Foundation of China (30572306), the State Administration of Traditional Chinese Medicine of China and Shanghai Leading Academic Discipline Project (T0302), and by the Shanghai Science and Technology Developing Foundation (03DZ19954-2). Statistical analyses were performed under the direction of statistician Ms Qiuhong.

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Authors and Affiliations

  1. Shanghai University of Traditional Chinese Medicine (TCM), 1200, Cailun Road, Shanghai, 201203, People’s Republic of China

    Ling Zhao, Xue-yong Shen, Jian-zi Wei, Hai-ping Deng, Lizhen Wang & Xiao-ying Zhao

  2. Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, People’s Republic of China

    Jian-ping Gao

  3. Fudan University, Shanghai, 200433, People’s Republic of China

    Guang-hong Ding

  4. Shanghai Research Center of Acupuncture & Meridian, Shanghai, 201203, People’s Republic of China

    Xue-yong Shen & Guang-hong Ding

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  1. Ling Zhao
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  8. Xiao-ying Zhao
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Correspondence to Xue-yong Shen.

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Zhao, L., Shen, Xy., Gao, Jp. et al. Effect of different LLLT on pituitrin-induced bradycardia in the rabbit. Lasers Med Sci 21, 61–66 (2006). https://doi.org/10.1007/s10103-006-0371-4

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  • DOI: https://doi.org/10.1007/s10103-006-0371-4

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