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OPAT for cellulitis: its benefits and the factors that predispose to longer treatment

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European Journal of Clinical Microbiology & Infectious Diseases Aims and scope Submit manuscript

Abstract

This retrospective study investigated the demographics and treatment outcomes of patients with cellulitis receiving outpatient parenteral antibiotic therapy (OPAT) between 2010 and 2014 in Cambridge University Hospitals. The rate of treatment failure (as indicated by the readmission to hospital) was low, at 5.5%. Risk factors associated with a longer duration of OPAT treatment included: immunosuppression, peripheral vascular disease, obesity, lymphoedema, previous cellulitis and diabetes.

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References

  1. Seaton R, Barr D (2013) Outpatient parenteral antibiotic therapy: principles and practice. Eur J Intern Med 24:617–623

    Article  CAS  PubMed  Google Scholar 

  2. Hitchcock J, Jepson A, Main J, Wickens H (2009) Establishment of an outpatient and home parenteral antimicrobial therapy service at a London teaching hospital: a case series. J Antimicrob Chemother 64(3):630–634

    Article  CAS  PubMed  Google Scholar 

  3. Figtree M, Konecny P, Jennings Z, Goh C, Krilis S, Miyakis S (2010) Risk stratification and outcome of cellulitis admitted to hospital. J Infect 60:431–439

    Article  CAS  PubMed  Google Scholar 

  4. Halilovic J, Heintz B, Brown J (2012) Risk factors for clinical failure in patients hospitalized with cellulitis and cutaneous abscess. J Infect 65:129–134

    Article  Google Scholar 

  5. Keeley V (2008) Lymphoedema and cellulitis: chicken or egg? Br J Dermatol 158:1175–1176

    Article  CAS  PubMed  Google Scholar 

  6. Halpern K, Holder R, Langford N (2008) Ethnicity and other risk factors for acute lower limb cellulitis: a UK-based prospective case–control study. Br J Dermatol 158:1288–1292

    Article  CAS  PubMed  Google Scholar 

  7. Lillie P, Andrews D, Eaves K, Darton T, Chapman A (2010) Baseline factors predicting the duration of intravenous antibiotic therapy for cellulitis in an outpatient setting. Eur J Clin Microbiol Infect Dis 29:347–349

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors would like to thank Sister Anna Mayhew, OPAT department, Addenbrooke’s Hospital, for help with the data collection of cellulitis patients using the service.

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Authors and Affiliations

  1. School of Clinical Medicine, University of Cambridge, Addenbrooke’s Hospital, Hills Road, Cambridge, CB2 0SP, UK

    J. Zhang

  2. Department of Infectious Diseases, Addenbrooke’s Hospital, Cambridge, CB2 0QQ, UK

    E. Moore & R. Bousfield

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  1. J. Zhang
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  2. E. Moore
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  3. R. Bousfield
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Correspondence to J. Zhang.

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Zhang, J., Moore, E. & Bousfield, R. OPAT for cellulitis: its benefits and the factors that predispose to longer treatment. Eur J Clin Microbiol Infect Dis 35, 1013–1015 (2016). https://doi.org/10.1007/s10096-016-2631-y

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  • DOI: https://doi.org/10.1007/s10096-016-2631-y

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