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Risk factor analysis of invasive liver abscess caused by the K1 serotype Klebsiella pneumoniae

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Abstract

The increasing prevalence of Klebsiella pneumoniae liver abscess in Asian countries is attributable to virulent strains of the K1 serotype. We investigated the risk factors for the K1 serotype K. pneumoniae liver abscess. A case-control study was performed using the database of a nationwide study of liver abscess in Korea. Multivariate logistic regression analysis was performed for 78 cases of the K1 serotype K. pneumoniae liver abscess and 81 controls with non-Klebsiella. Diabetes mellitus was the significant risk factor (OR 2.13; 95% CI 1.026 ~ 4.428; P = 0.042) for the K1 serotype K. pneumoniae liver abscess. Biliary disorders had a strong negative association (OR 0.18; 95% CI 0.078 ~ 0.410; P < 0.001). This study suggests that diabetes mellitus is a more significant risk factor for the K1 serotype K. pneumoniae liver abscess than for the non-Klebsiella liver abscess.

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Acknowledgements

The Korean Study Group for Liver Abscess is represented by Doo Ryeon Chung (Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea), Seung Soon Lee and Choong Kee Park (Hallym University Sacred Heart Hospital), Joong Sik Eom and Jae Seok Kim (Kangdong Sacred Heart Hospital), Heung Jeong Woo (Hangang Sacred Heart Hospital), Myung Seok Lee (Kangnam Sacred Heart Hospital), Hong Bin Kim (Seoul National University Bundang Hospital), Myoung-don Oh (Seoul National University Hospital), Hee Jung Choi (Ewha Womans University MokDong Hospital), Jae-Hoon Song (Samsung Medical Center), Jin Hong Yoo (Catholic University Medical College, Holy Family Hospital), Seong Heon Wie (Catholic University Medical College, St. Vincent’s Hospital), Young Hwa Choi and Wee Gyo Lee (Ajou University Hospital), Jin Soo Lee, Moon Hyun Chung (Inha University Hospital), Yeon Sook Kim (Chungnam National University Hospital), Sang Won Park (Dankook University Hospital), Hee Bok Chae (Chungbuk National University Hospital), Hyun Ha Chang and Shin Woo Kim (Kyungpook National University Hospital), Hyuk Lee (Dong-A University Medical Center), Mi Sook Lee (Ulsan University Hospital), Sook In Jung (Chonnam National University Hospital), Byung-Cheol Song (Cheju National University Hospital), and Dong Joon Kim (Chunchon Sacred Heart Hospital).

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Author notes

  1. S. W. Park

    Present address: Seoul National University Boramae Hospital, Seoul, Korea

Authors and Affiliations

  1. Division of Infectious Diseases, Hallym University Sacred Heart Hospital, Anyang-si, Korea

    J.-K. Kim

  2. Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 ILwon-dong, Gangnam-gu, Seoul, 135-710, Korea

    D. R. Chung

  3. Catholic University Medical College, St. Vincent’s Hospital, Suwon, Korea

    S. H. Wie

  4. Catholic University Medical College, Holy Family Hospital, Bucheon-si, Korea

    J. H. Yoo

  5. Dankook University Hospital, Cheonan-si, Korea

    S. W. Park

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  1. J.-K. Kim
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  4. J. H. Yoo
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  5. S. W. Park
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the Korean Study Group for Liver Abscess

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Correspondence to D. R. Chung.

Additional information

Contributing members of the Korean Study Group for Liver Abscess are listed in the Acknowledgments.

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Kim, JK., Chung, D.R., Wie, S.H. et al. Risk factor analysis of invasive liver abscess caused by the K1 serotype Klebsiella pneumoniae . Eur J Clin Microbiol Infect Dis 28, 109–111 (2009). https://doi.org/10.1007/s10096-008-0595-2

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  • DOI: https://doi.org/10.1007/s10096-008-0595-2

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