Skip to main content
Log in

Synergy testing of multidrug resistant Acinetobacter baumanii against tigecycline and polymyxin using an E-test methodology

  • Brief Report
  • Published:
European Journal of Clinical Microbiology & Infectious Diseases Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Rice LB (2006) Challenges in identifying new antimicrobial agents effective for treating infections with Acinetobacter baumanii and Pseudomonas aeruginosa. Clin Infect Dis 43:S100–S105

    Article  PubMed  CAS  Google Scholar 

  2. Pachon-Ibanez ME, Jiminez-Mejias ME, Pichardo C, Llanos AC, Pachon J (2004) Activity of tigecycline against Acinetobacter baumannii strains, including those resistant to imipenem. Antimicro Agents Chemother 48:4479–4481

    Article  CAS  Google Scholar 

  3. Falagas MD, Kasiakou SK (2005) Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin Infect Dis 40:1333–1341

    Article  PubMed  CAS  Google Scholar 

  4. Rahal JJ (2006) Novel antibiotic combinations against infections with almost completely resistant Pseudomonas aeruginosa and Acinetobacter species. Clin Infect Dis 43:S95–S99

    Article  PubMed  CAS  Google Scholar 

  5. Petersen PJ, Labthavikul P, Jones CH, Bradford PA (2006) In vitro antibacterial activities of tigecycline in combination with other antibicrobial agents determined by chequerboard and time-kill kinetic analysis. J Antimicrob Chemo 57:573–576

    Article  CAS  Google Scholar 

  6. Baker CN, Stocker SA, Culver DH, Thornsberry C (1991) Comparison of the E Test to agar dilution, broth microdilution, and agar diffusion susceptibility testing techniques by using a special challenge set of bacteria. J Clin Microbiol 29:533–538

    PubMed  CAS  Google Scholar 

  7. White RL, Burgess DS, Manduru M, Bosso JA (1996) Comparison of three different in vitro methods of detecting synergy: Time-kill, checkerboard, and E test. Antimicro Agents Chemother 40:1914–1918

    CAS  Google Scholar 

  8. Bonapace CR, White RL, Friedrich LV, Bosso JA (2000) Evaluation of antibiotic synergy against Acinetobacter baumannii: a comparison with E-test, time-kill and checkerboard method. Diagn Microbiol Infect Dis 38:43–50

    Article  PubMed  CAS  Google Scholar 

  9. Navon-Venezia S, Leavitt A, Carmeli Y (2007) High tigecycline resistance in multidrug-resistant Acinetobacter baumannii. J Antimicrob Chemother 59:772–774

    Article  PubMed  CAS  Google Scholar 

  10. Ruzin A, Keeney D, Bradford PA (2007) AddABC multidrug efflux pump is associated with decreased susceptibility to tigecycline in Acinetobacter calcoaceticusAcinetobacter baumannii complex. J Antimcirob Chemother 59:1001–1004

    Article  CAS  Google Scholar 

  11. Scheetz MH, Qi C, Warren JR et al (2007) In vitro activities of various antimicrobials alone and in combination with tigecycline against carbapenem-intermediate or resistant Acinetobacter baumannii. Antimicrob Agents Chemother 51:1621–1626

    Article  PubMed  CAS  Google Scholar 

Download references

Transparency Declaration

None to declare

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M. Sands.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sands, M., McCarter, Y. & Sanchez, W. Synergy testing of multidrug resistant Acinetobacter baumanii against tigecycline and polymyxin using an E-test methodology. Eur J Clin Microbiol Infect Dis 26, 521–522 (2007). https://doi.org/10.1007/s10096-007-0330-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10096-007-0330-4

Keywords

Navigation