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Candida species distribution in bloodstream cultures in Lyon, France, 1998–2001

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Abstract

In order to determine the types of Candida spp. isolated from bloodstream cultures in Lyon, France, a retrospective study of isolates collected at five different bacteriology laboratories from 1998 to 2001 was conducted. During this period Candida spp. were isolated from 190 patients hospitalized in the internal medicine (32%), hematology (23%) and surgery (23%) wards, and in intensive care units (22%). C. albicans was the leading cause of Candida infection (49.5%), followed by C. glabrata (12.6%) and C. parapsilosis (12.1%). Among the onco-hematology patients, the major cause of candidemia was C. krusei (34%), followed by C. albicans (19%), while these two species were identified in 4% and 59% of patients in the other wards, respectively. In the single onco-hematology ward that was specialized in treating acute myeloid leukemia, 14 C. krusei isolates were identified in this study, which contrasts with the single C. krusei isolate recorded between 1992 and 1996. Since C. krusei has inherent resistance to the antifungal agent fluconazole, prophylactic use of fluconazole in these patients was investigated, but no relationship between these two parameters was found.

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Acknowledgments

We would like to thank S. Tigaud, P. Girardo, M. de Monclos, Y. Brun, A.M. Freydière and S. Robin for their precious help in collecting data from their databases, B. Premilleux and B. Roehrig for complementary data analyses and M. Haugh for the English corrections

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  1. Laboratoire de Parasitologie et Mycologie Médicale, Hôpital Edouard Herriot, Hospices Civils de Lyon, 8 avenue Rockefeller, 69373, Lyon Cedex 08, France

    D. Martin, F. Persat, M.-A. Piens & S. Picot

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  1. D. Martin
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  2. F. Persat
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  3. M.-A. Piens
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  4. S. Picot
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Correspondence to F. Persat.

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Martin, D., Persat, F., Piens, MA. et al. Candida species distribution in bloodstream cultures in Lyon, France, 1998–2001. Eur J Clin Microbiol Infect Dis 24, 329–333 (2005). https://doi.org/10.1007/s10096-005-1321-y

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