Abstract
Strokes are the paradigmatic example of the sudden impairment of the cerebral regulation of cardiac autonomic regulation. Although several aspects of dysautonomic cardiovascular regulation post stroke remain unanswered, there has been a wealth of research in this area in the last decade. In this article, we present a state-of-the-art review on the anatomical and functional organization of cardiovascular autonomic regulation, and the pathophysiology, incidence, time course, diagnosis, clinical aspects, prognosis, and management of post-stroke cardiovascular autonomic dysfunction.
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LAS is supported by the Kathleen & Dr. Henry Barnett Research Chair in Stroke Research (Western University, London, Canada), the Edward and Alma Saraydar Neurosciences Fund (London Health Sciences Foundation, London, Canada), and the Opportunities Fund of the Academic Health Sciences Centre Alternative Funding Plan of the Academic Medical Organization of Southwestern Ontario (AMOSO) (Ontario, Canada). None of these funding sources had a role in the design or results of this study.
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LAS: speaker and consulting honoraria from Boehringer Ingelheim, Pfizer, Bayer and Gore; research grants from Boehringer Ingelheim and Bayer. LAS is member of the Editorial Board of Neurology and Stroke journals, and the World Stroke Academy (Webinar platform of the World Stroke Organization). The remaining authors have nothing to disclose.
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Jimenez-Ruiz, A., Racosta, J.M., Kimpinski, K. et al. Cardiovascular autonomic dysfunction after stroke. Neurol Sci 42, 1751–1758 (2021). https://doi.org/10.1007/s10072-021-05128-y
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DOI: https://doi.org/10.1007/s10072-021-05128-y