Abstract
One hundred-eighteen spinocerebellar ataxia type 2 patients from 35 distinct families personally observed between 1973 and 2016 were retrospectively reviewed. The time point of data collection was 1 January 2017. Thirty-one patients were confined to wheelchair. The median time to wheelchair was 21 years (95% CI, 17.5–24.6). Thirty-seven patients were deceased. The median time to death was 25 years (95% CI, 22.9–27.1). CAG repeat number and ataxia score at first visit influenced the time to wheelchair and death.
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Antenora, A., Bruzzese, D., Lieto, M. et al. Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy. Neurol Sci 39, 1857–1860 (2018). https://doi.org/10.1007/s10072-018-3504-1
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DOI: https://doi.org/10.1007/s10072-018-3504-1