Abstract
Chronic headaches have increasingly become a focus within the field of head pain. Most of the patients with frequent headache eventually overuse their medications, and if it happens [the percentage is approximately 4%], the diagnosis of chronic migraine with medication-overuse headache is clinically important, because patients rarely respond to preventive medications while overusing acute medications. This kind of headache is recognized as a biobehavioral disorder, a complex condition wherein emotion and pain are intermingled. Properly treating medication overuse with adequate strategies by different and specific steps are essential components for helping these patients to improve and for preventing relapses. The clinical experience performed at our Headache Unit, the necessity of withdrawal, different treatment schedules, and different treatment strategies of our center were discussed.
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References
Diener HC, Limmroth V (2004) Medication-overuse headache: a worldwide problem. Lancet Neurol 3:475–483
Meskunas CA, Tepper SJ, Rapoport AM, Sheftell FD, Bigal ME (2006) Medications associated with probable medication overuse headache reported in a tertiary care headache center over a 15-year period. Headache 46:766–772
Grazzi L, Andrasik F, Usai S, Bussone G (2009) Treatment of chronic migraine with medication overuse: is drug withdrawal crucial? Neurol Sci 30(S1):85–88
Andrasik F, Grazzi l, Usai S, Buse DC, Bussone G (2009) Non-pharmacological approaches to treating crhonic migraine with medication overuse. Neurol Sci 30(S1):89–94
Grazzi F, Andrasik F, Usai S, Bussone G (2008) Headache with medication overuse: treatment strategies and proposal of relapse prevention. Neurol Sci 29:93–98
Saper JR, Hamel RL, Lake AE III (2005) Medication overuse headache (MOH) is a biobehavioural disorder. Cephalalgia 25:545–546
Lake AE III (2006) Medication overuse headache: biobehavioral issues and solutions. Headache 46(Suppl 3):S88–S97
Grazzi L, Andrasik F, D’Amico D, Leone M, Usai S, Kass S, Bussone G (2002) Behavioral and pharmacologic treatment of transformed migraine with analgesic overuse: outcome at 3 years. Headache 42:483–490
Bigal ME, Lipton RB (2006) Modifiable risk factors for migraine progression. Headache 46:1334–1343
Montagna P, Pierangeli G, Cortelli P (2009) The primary headaches as a reflection of genetic darwinian adaptive behavioral responses. Headache 50:273–289
Calabresi P, Cupini ML (2005) Medication-overuse headache: similarities with drug addiction. Trends Pharmacol Sci 28(2):62–68
Grazzi L, Chiapparini L, Ferraro S, Usai S, Andrasik F, Mandelli ML, Bruzzone MG, Bussone G (2010) Chronic migraine with medication overuse pre-post withdrawal of symptomatic medication: clinical results and FMRI correlations. Headache 50:998–1004
Rothrock JF, Parada VA, Sims C et al (2006) The impact of intensive patient education on clinical outcome in a clinic-based migraine population. Headache 46:726–731
Dodick D, Silberstein S (2008) How clinicians can detect, prevent, and treat medication overuse headache. Cephalalagia 28(11):1207–1217
Aurora S, Dodick D, Turkel C et al (2010) Onabotulinum A for treatment of chronic migraine : Results from the double blind, randomized, placebo-controlled phase of the PREEMPT 1 trial. Cephalalgia 40(7):793–803
Diener HC, Dodick D, Aurora S (2010) Onabotulinum A for treatment of chronic migarine: pooled results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 2 trial. Cephalalagia 30(7):804–814
Rains JC, Penzien DB, Lipchik GL (2006) Behavioral facilitation of medical treatment for headache–Part II: Theoretical models and behavioral strategies for improving adherence. Headache 46:1395–1403
Jensen MP (2002) Enhancing motivations to change in pain treatment. In: Turk DC, Gatchel RJ (eds) Psychological approaches to pain management: a practitioner’s handbook, 2nd edn. Guilford Press, New York, pp 71–93
Miller WR (1996) Motivational interviewing: research, practice, and puzzles. Addict Behav 21:835–842
Andrasik F (2007) What does the evidence show? Efficacy of behavioural treatments for recurrent headaches in adults. Neurol Sci 28:S70–S77
Nestoriuc Y, Martin A, Rief W, Andrasik F (2008) Biofeedback treatment for headache disorders: a comprehensive efficacy review. Appl Psychophysiol Biofeedback 33:125–140
Jette N, Patten S, Williams J et al (2008) Comorbidity of migraine and psychiatric disorders: a national population-based study. Headache 48:501–516
Smitherman TA, Maizels M, Penzien DB (2008) Headache chronification: Screening and behavioral management of comorbid depressive and anxiety disorders. Headache 48:45–50
Lipchik GL, Smitherman TA, Penzien DB, Holroyd KA (2006) Basic principles and techniques of cognitive-behavioral therapies for comorbid psychiatric symptoms among headache patients. Headache 46(Suppl 3):S119–S132
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Grazzi, L., Bussone, G. What future for treatment of chronic migraine with medication overuse?. Neurol Sci 32 (Suppl 1), 19–22 (2011). https://doi.org/10.1007/s10072-011-0553-0
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DOI: https://doi.org/10.1007/s10072-011-0553-0