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Air pollution positively correlates with daily stroke admission and in hospital mortality: a study in the urban area of Como, Italy

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Abstract

Some current evidences suggest that stroke incidence and mortality may be higher in elevated air pollution areas. Our study examined the hypothesis of a correlation between air pollution level and ischemic stroke admission and in Hospital mortality in an urban population. Data on a total of 759 stroke admissions and 180 deaths have been obtained over a 4-year period (2000–2003). Five air ambient particles have been studied. A general additive model estimating Poisson distribution has been used, adding meteorological variables as covariates. NO2 and PM10 were significantly associated with admission and mortality (P value < 0.05) and with estimated RR of 1.039 (95% CI 1.066–1.013) and 1.078 (95% CI 1.104–1.052) for hospital admission at 2- and 4-day lags, respectively. In conclusion, this study suggests an association between short-term outdoor air pollution exposure and ischemic stroke admission and mortality.

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References

  1. Brook RD, Franklin B, Cascio W, Hong Y, Howard G, Lipsett M, Luepker R, Mittleman M, Samet J, Smith SC Jr, Tager I (2004) Expert Panel on Population and Prevention Science of the American Heart Association. Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on population and prevention science of the American Heart Association. Circulation 109:2655–2671

    Article  PubMed  Google Scholar 

  2. Miller KA, Siscovick DS, Sheppard L, Shepherd K, Sullivan JH, Anderson GL, Kaufman JD (2007) Long-term exposure to air pollution and incidence of cardiovascular events in women. New Eng J Med 356:447–458

    Article  CAS  PubMed  Google Scholar 

  3. Tsai SS, Goggins WB, Chiu HF, Yang CY (2003) Evidence for an association between air pollution and daily stroke admissions in Kaohsiung, Taiwan. Stroke 34:2612–2616

    Article  CAS  PubMed  Google Scholar 

  4. Hong YC, Lee JT, Kim LH, Kwon HJ (2002) Air pollution. A new risk factor in ischemic stroke mortality. Stroke 33:2165–2169

    Article  CAS  PubMed  Google Scholar 

  5. Maheswaran R, Haining RP, Brindley P, Law J, Pearson T, Fryers PR, Wise S, Campbell MJ (2005) Outdoor air pollution and stroke in Sheffield, United Kingdom. A small-area level geographical study. Stroke 36:239–243

    Article  PubMed  Google Scholar 

  6. Hoek G, Brunekreef B, Goldbohm S, Fisher P, van den Brandt PA (2003) Association between mortality and indicators of traffic-related air pollution in the Netherlands: a cohort study. Lancet 360:1203–1209

    Article  Google Scholar 

  7. Piver WT, Ando M, Ye F, Portier CJ (1999) Temperature and air pollution as risk factors for heat stroke in Tokio, July and August 1980–1995. Environ Health Perspect 107:911–916

    Article  CAS  PubMed  Google Scholar 

  8. Poloniecki JD, Atkinson RW, de Leon AP, Anderson HR (1997) Daily time series for cardiovascular hospital admissions and previous day’s air pollution in London, UK. Occup Environ Med 54:535–540

    Article  CAS  PubMed  Google Scholar 

  9. Le Tertre A, Medina S, Samoli E, Forsberg B, Mechelozzi P, Boumghar A, Vonk JM, Bellini A, Atkinson R, Ayres JG, Sunyer J, Schwartz J, Katsouyanni K (2002) Short term effects of particulate air pollution on cardiovascular diseases in eight European cities. J Epidemiol Community Health 56:773–779

    Article  CAS  PubMed  Google Scholar 

  10. Zhang J, Yu KF (1998) What’s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 280:1690–1691

    Article  CAS  PubMed  Google Scholar 

  11. Biggeri A, Bellini P, Terracini B (2001) Meta-analysis of the Italian studies on short-term effects of air pollution. Epidem Prevent Suppl 2:2–71

    Google Scholar 

  12. Wellenius GA, Schwartz J, Mittleman MA (2005) Air pollution and hospital admissions for ischemic and hemorrhagic stroke among medicare benificiaries. Stroke 36:2549–2553

    Article  CAS  PubMed  Google Scholar 

  13. Frampton MW, Stewart JC, Oberdörster G, Morrow PE, Chalupa D, Pietropaoli AP, Frasier LM, Speers DM, Cox C, Huang LS, Utell MJ (2006) Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environ Health Perspect 114(1):51–58

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Neurology Department, Sant’Anna Hospital, Via Napoleona 60, 22100, Como, Italy

    Simone Vidale & M. Arnaboldi

  2. Statistic Sciences Department, Cattolica Sacro Cuore University, Milan, Italy

    A. Bonanomi

  3. Neurology Department, Valduce Hospital, Como, Italy

    M. Guidotti

  4. Neurology Department, Niguarda Ca’ Granda Hospital, Milan, Italy

    R. Sterzi

Authors
  1. Simone Vidale
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  2. A. Bonanomi
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  3. M. Guidotti
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  4. M. Arnaboldi
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  5. R. Sterzi
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Correspondence to Simone Vidale.

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Vidale, S., Bonanomi, A., Guidotti, M. et al. Air pollution positively correlates with daily stroke admission and in hospital mortality: a study in the urban area of Como, Italy. Neurol Sci 31, 179–182 (2010). https://doi.org/10.1007/s10072-009-0206-8

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  • DOI: https://doi.org/10.1007/s10072-009-0206-8

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