Abstract
Vitamin B12 deficiency causes haematological, gastrointestinal and neurological diseases. Subacute combined degeneration (SCD) of the spinal cord is characterised by degeneration of the posterior and lateral columns. We report a case of SCD associated with nitrous oxide anaesthesia.
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Layzer RB (1978) Myeloneuropathy after prolonged exposure to nitrous oxide. Lancet 2:1227–1230
Ilniczky S, Jelencsik I, Kenéz J, Szirmai I (2002) MR findings in subacute combined degeneration of the spinal cord caused by nitrous oxide anaesthesia-two cases. Eur J Neurol 9:101–104
Sesso RM, Iunes Y, Melo AC (1999) Myeloneuropathy following nitrous oxide anesthesia in a patient with macrocytic anaemia. Neuroradiology 41:588–590
Katsaros VK, Glocker FX, Hemmer B, Schumacher M (1998) MRI of spinal cord and brain lesions in subacute combined degeneration. Neuroradiology 40:716–719
Cartner M, Sinnott M, Silburn P (2007) Paralysis caused by “nagging”. Med J Aust 187:366–367
Beltramello A, Puppini G, Cerini R et al (1998) Subacute combined degeneration of the spinal cord after nitrous oxide anaesthesia: role of magnetic resonance imaging. J Neurol Neurosurg Psychiatry 64:563–564
Singer MA, Lazaridis C, Nations SP, Wolfe GI (2008) Reversible nitrous oxide-induced myeloneuropathy with pernicious anemia: case report and literature review. Muscle Nerve 37:125–129
Ng J, O’Grady G, Pettit T, Frith R (2003) Nitrous oxide use in first-year students at Auckland University. Lancet 361:1349–1350
Karantanas AH, Markonis A, Bisbiyiannis G (2000) Subacute combined degeneration of the spinal cord with involvement of the anterior columns: a new MRI finding. Neuroradiology 42:115–117
Ravina B, Loevner LA, Bank W (2000) MR findings in subacute combined degeneration of the spinal cord: a case of reversible cervical myelopathy. AJR Am J Roentgenol 174:863–865
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Renard, D., Dutray, A., Remy, A. et al. Subacute combined degeneration of the spinal cord caused by nitrous oxide anaesthesia. Neurol Sci 30, 75–76 (2009). https://doi.org/10.1007/s10072-009-0013-2
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DOI: https://doi.org/10.1007/s10072-009-0013-2