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Antioxidant effect of peony seed oil on aging mice

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Abstract

d-galactose was injected into mice of ages 4–5 months, and peony seed oil was administered using an oral gavage to assess its possible anti-aging functions. The content of malondialdehyde (MDA) and the activities of monoamine oxidase (MAO), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) in the brain and liver of these mice were determined using biochemical kits. The significance of the differences in the content of the components associated with aging and anti-aging among each group was analyzed statistically. The MDA content and activities of MAO in the brain and liver of mice in the peony seed oil group were significantly lower than those in the aging group. The activities of GSH-Px, Cu/Zn-SOD, and Mn-SOD in the brain and liver of mice in the peony seed oil group were very significantly higher than those in the aging group. Peony seed oil was determined to have an obvious anti-aging function.

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Acknowledgements

This work was supported by the Research Fund for Science and Technology Project of Hunan Province in China (Grant No. 2016NK2136).

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Authors and Affiliations

  1. School of Chemistry and Bioengineering, Changsha University of Science and Technology, Changsha, 410004, China

    Xiao-Miao Han, Su-Xi Wu & Mei-Fang Wu

  2. Haorui Biological Technology Co., Ltd, Changsha, 410004, China

    Su-Xi Wu

  3. School Hospital, Changsha University of Science and Technology, Changsha, 410004, China

    Xue-Feng Yang

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  1. Xiao-Miao Han
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Correspondence to Su-Xi Wu.

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Han, XM., Wu, SX., Wu, MF. et al. Antioxidant effect of peony seed oil on aging mice. Food Sci Biotechnol 26, 1703–1708 (2017). https://doi.org/10.1007/s10068-017-0225-9

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  • DOI: https://doi.org/10.1007/s10068-017-0225-9

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