Abstract:
Forty-nine patients diagnosed as having gonarthrosis were given intra-articular treatment with hyaluronic acid (Adant or Hyalgan) in a blind randomised study. We concluded that the efficacy with Adant at 3 months after treatment was greater than with Hyalgan (50% versus 21.1%). The maximum improvement with hyaluronic acid was seen at 5 weeks in 75.4% and the adverse effects consisted of pain in the infiltration side which was almost twice as great with Adant (16.3%).
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Received: 23 July 1999 / Accepted: 10 December 1999
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Román, J., Chismol, J., Morales, M. et al. Intra-articular Treatment with Hyaluronic Acid. Comparative Study of Hyalgan and Adant. Clin Rheumatol 19, 204–206 (2000). https://doi.org/10.1007/s100670050157
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DOI: https://doi.org/10.1007/s100670050157