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The impact of peer victimization and psychological symptoms on quality of life in children and adolescents with systemic lupus erythematosus

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Abstract

There is no documentation about the association between peer victimization, psychological status, and quality of life (QOL) in children and adolescents with systemic lupus erythematosus (SLE). The aim of this study was to evaluate the association between peer victimization, psychological symptoms, and QOL in a cohort of children and adolescents with SLE. Forty-one patients (aged 9–18 years) participated in this study. The control group (n = 49) was composed of healthy children and adolescents from local community. Questionnaires were used to evaluate the peer victimization, psychological status, and QOL of children and adolescents with and without SLE. No significant difference was found between the study and control groups for peer victimization, depression, state and trait anxiety, and QOL scores. The peer victimization, depression, anxiety, and self-esteem scores were negatively correlated with psychosocial and total subscale scores of QOL in the study group. According to regression analyses, trait anxiety had a negative predictive effect on the physical health domain scores of QOL, whereas trait anxiety and peer victimization had a negative effect on the psychosocial domain and total scores of QOL in the SLE patients. This study suggests that trait anxiety and peer victimization are risk factors for poor QOL in adolescents with SLE.

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References

  1. Malattia C, Martini A (2013) Paediatric-onset systemic lupus erythematosus. Best Pract Res Clin Rheumatol 27:351–362

    Article  PubMed  Google Scholar 

  2. Meszaros ZS, Perl A, Faraone SV (2012) Psychiatric symptoms in systemic lupus erythematosus: a systematic review. J Clin Psychiatry 73:993–1001

    Article  PubMed  Google Scholar 

  3. Jones JT, Cunningham N, Kashikar-Zuck S, Brunner HI (2016) Pain, fatigue, and psychological impact on health-related quality of life in childhood-onset lupus. Arthritis Care Res (Hoboken) 68:73–80

    Article  Google Scholar 

  4. Brunner HI, Higgins GC, Wiers K, Lapidus SK, Olson JC, Onel K, Punaro M, Ying J, Klein-Gitelman MS, Seid M (2009) Health-related quality of life and its relationship to patient disease course in childhood-onset systemic lupus erythematosus. J Rheumatol 36:1536–1545

    Article  PubMed  Google Scholar 

  5. Ruperto N, Buratti S, Duarte-Salazar C, Pistorio A, Reiff A, Bernstein B, Maldonado-Velázquez MR, Beristain-Manterola R, Maeno N, Takei S, Falcini F, Lepore L, Spencer CH, Pratsidou-Gertsi P, Martini A, Ravelli A (2004) Health-related quality of life in juvenile onset systemic lupus erythematosus and its relationship to disease activity and damage. Arthritis Rheum 51:458–464

    Article  PubMed  Google Scholar 

  6. Ji L, Lili S, Jing W, Yanyan H, Min W, Juan X, Hongmei S (2012) Appearance concern and depression in adolescent girls with systemic lupus erythematous. Clin Rheumatol 31:1671–1675

    Article  PubMed  Google Scholar 

  7. Hiraki LT, Benseler SM, Tyrrell PN, Hebert D, Harvey E, Silverman ED (2008) Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study. J Pediatr 152:550–556

    Article  PubMed  Google Scholar 

  8. Bader-Meunier B, Armengaud JB, Haddad E, Salomon R, Deschênes G, Koné-Paut I, Leblanc T, Loirat C, Niaudet P, Piette JC, Prieur AM, Quartier P, Bouissou F, Foulard M, Leverger G, Lemelle I, Pilet P, Rodière M, Sirvent N, Cochat P (2005) Initial presentation of childhood-onset systemic lupus erythematosus: a French multicenter study. J Pediatr 146:648–653

    Article  CAS  PubMed  Google Scholar 

  9. Magin P (2013) Appearance-related bullying and skin disorders. Clin Dermatol 31:66–71

    Article  PubMed  Google Scholar 

  10. Zhu J, Yu C, Zhang W, Bao Z, Jiang Y, Chen Y, Zhen S (2016) Peer victimization, deviant peer affiliation and impulsivity: predicting adolescent problem behaviors. Child Abuse Negl 58:39–50

    Article  PubMed  Google Scholar 

  11. Begle AM, Hanson RF, Danielson CK, McCart MR, Ruggiero KJ, Amstadter AB, Resnick HS, Saunders BE, Kilpatrick DG (2011) Longitudinal pathways of victimization, substance use, and delinquency: findings from the National Survey of Adolescents. Addict Behav 36:682–689

    Article  PubMed  PubMed Central  Google Scholar 

  12. Ostrov JM (2010) Prospective associations between peer victimization and aggression. Child Dev 81:1670–1677

    Article  PubMed  Google Scholar 

  13. Hochberg MC (1997) Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 40:1725.

  14. Brunner HI, Feldman BM, Bombardier C, Silverman ED (1999) Sensitivity of the systemic lupus erythematosus disease activity index, British isles lupus assessment group index, and systemic lupus activity measure in the evaluation of clinical change in childhood-onset systemic lupus erythematosus. Arthritis Rheum 42:1354–1360

    Article  CAS  PubMed  Google Scholar 

  15. Gladman DD, Ibanez D, Urowitz MB (2002) Systemic lupus erythematosus disease activity index 2000. J Rheumatol 29:288–291

    PubMed  Google Scholar 

  16. Maynard H, Joseph S (2000) Development of the multidimensional victimization scale. Aggress Behav 26:169–178

    Article  Google Scholar 

  17. Gultekin Z, Sayil M (2005) A study of reliability and validity of the peer victimization scale. Turkish Psychological Articles 8:47–61 [In Turkish]

    Google Scholar 

  18. Öy B (1991) Children’s depression inventory: validity and reliability study. Turk Psikiyatri Derg 2:132–136 [In Turkish]

    Google Scholar 

  19. Özusta S (1995) Turkish standardization, reliability and validity of State Trait Anxiety Inventory for children. Turk J Psychol 10:32–44 [In Turkish]

    Google Scholar 

  20. Varni JW, Seid M, Rode CA (1999) The PedsQL: measurement model for the pediatric quality of life inventory. Med Care 37:126–139

    Article  CAS  PubMed  Google Scholar 

  21. Cakın Memik N, Agaoglu B, Coskun A, Uneri OS, Karakaya I (2007) The validity and reliability of the Turkish pediatric quality of life inventory for children 13–18 years old. Turk Psikiyatri Derg 18:353–363 [In Turkish]

    PubMed  Google Scholar 

  22. Cuhadaroglu F (1986) Self-esteem in adolescents. Hacettepe University, Turkey, Doctoral dissertation

    Google Scholar 

  23. Wolke D, Woods S, Bloomfield L, Karstadt L (2001) Bullying involvement in primary school and common health problems. Arch Dis Child 85(3):197–201

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Rueger SY, Jenkins LN (2014) Effects of peer victimization on psychological and academic adjustment in early adolescence. Sch Psychol Q 29(1):77–88

    Article  PubMed  Google Scholar 

  25. Wu L, Zhang D, Su Z, Hu T (2015) Peer victimization among children and adolescents: a meta-analytic review of links to emotional maladjustment. Clin Pediatr (Phila) 54(10):941–955

    Article  Google Scholar 

  26. van Weelden M, Queiroz LB, Lourenço DM, Kozu K, Lourenço B, Silva CA (2016) Alcohol, smoking and illicit drug use in pediatric systemic lupus erythematosus patients. Rev Bras Reumatol (Rio J) 56:228–234

    Article  Google Scholar 

  27. Sentenac M, Gavin A, Gabhainn SN, Molcho M, Due P, Ravens-Sieberer U, Matos MG, Malkowska-Szkutnik A, Gobina I, Vollebergh W, Arnaud C, Godeau E (2013) Peer victimization and subjective health among students reporting disability or chronic illness in 11 Western countries. Eur J Pub Health 23:421–426

    Article  Google Scholar 

  28. Janicke DM, Marciel KK, Ingerski LM, Novoa W, Lowry KW, Sallinen BJ, Silverstein JH (2007) Impact of psychosocial factors on quality of life in overweight youth. Obesity (Silver Spring) 15:1799–1807

    Article  Google Scholar 

  29. Storch EA, Lewin A, Silverstein JH, Heidgerken AD, Strawser MS, Baumeister A, Geffken GR (2004) Peer victimization and psychosocial adjustment in children with type 1 diabetes. Clin Pediatr 43:467–471

    Article  Google Scholar 

  30. Jarpa E, Babul M, Calderón J, González M, Martínez ME, Bravo-Zehnder M, Henríquez C, Jacobelli S, González A, Massardo L (2011) Common mental disorders and psychological distress in systemic lupus erythematosus are not associated with disease activity. Lupus 20:58–66

    Article  CAS  PubMed  Google Scholar 

  31. Demirkaya E, Bilginer Y, Aktay-Ayaz N, Yalnizoğlu D, Karli-Oğuz K, Işikhan V, Türker T, Topaloğlu R, Beşbaş N, Bakkaloğlu A, Ozen S (2008) Neuropsychiatric involvement in juvenile systemic lupus erythematosus. Turk J Pediatr 50:126–131

    PubMed  Google Scholar 

  32. Knight A, Weiss P, Morales K, Gerdes M, Gutstein A, Vickery M, Keren R (2014) Depression and anxiety and their association with healthcare utilization in pediatric lupus and mixed connective tissue disease patients: a cross-sectional study. Pediatr Rheumatol Online J 12:42

    Article  PubMed  PubMed Central  Google Scholar 

  33. Kohut SA, Williams T, Jayanthikumar J, Landolt-Marticorena C, Lefebvre A, Silverman E, Levy DM (2013) Depressive symptoms are prevalent in childhood-onset systemic lupus erythematosus (cSLE). Lupus 22:712–720

    Article  PubMed  Google Scholar 

  34. Louthrenoo O, Krairojananan J, Chartapisak W, Opastirakul S (2012) Psychosocial functioning of children with systemic lupus erythematosus. J Paediatr Child Health 48:1091–1094

    Article  PubMed  Google Scholar 

  35. Tamayo T, Fischer-Betz R, Beer S, Winkler-Rohlfing B, Schneider M (2010) Factors influencing the health related quality of life in patients with systemic lupus erythematosus: long-term results (2001-2005) of patients in the German Lupus Erythematosus Self-Help Organization (LULA Study). Lupus 19:1606–1613

    Article  CAS  PubMed  Google Scholar 

  36. Khanna S, Pal H, Pandey RM, Handa R (2004) The relationship between disease activity and quality of life in systemic lupus erythematosus. Rheumatology (Oxford) 43:1536–1540

    Article  CAS  Google Scholar 

  37. Houghton KM, Tucker LB, Potts JE, McKenzie DC (2008) Fitness, fatigue, disease activity, and quality of life in pediatric lupus. Arthritis Rheum 59:537–545

    Article  PubMed  Google Scholar 

  38. Bahali AG, Bahali K, Biyik Ozkaya D, Bilgic A, Su O, Onsun N (2016) The associations between peer victimization, psychological symptoms and quality of life in adolescents with acne vulgaris. J Eur Acad Dermatol Venereol 30(12):e184–e186

    Article  CAS  PubMed  Google Scholar 

  39. Papadimitraki ED, Isenberg DA (2009) Childhood- and adult-onset lupus: an update of similarities and differences. Expert Rev Clin Immunol 5(4):391–403

    Article  PubMed  Google Scholar 

  40. Drozdowicz LB, Bostwick JM (2014) Psychiatric adverse effects of pediatric corticosteroid use. Mayo Clin Proc 89(6):817–834

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

We wish to thank all the patients who participated in this study and their parents and staff of the participating center.

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Authors and Affiliations

  1. Department of Pediatrics, Medical Faculty, Bezmialem Vakif University, Istanbul, Turkey

    Selcuk Uzuner

  2. Department of Pediatric Rheumatology, Medical Faculty of Cerrahpasa, Istanbul University, Istanbul, Turkey

    Sezgin Sahin, Amra Adrovic, Kenan Barut & Ozgur Kasapcopur

  3. Department of Child and Adolescent Psychiatry, Medical Faculty of Cerrahpasa, Istanbul University, Istanbul, Turkey

    Gizem Durcan

  4. Department of Child and Adolescent Psychiatry, Neurology and Neurosurgery, Bakirkoy Research and Training Hospital for Psychiatry, 34147, Istanbul, Turkey

    Ali Guven Kilicoglu & Kayhan Bahali

  5. Department of Child and Adolescent Psychiatry, Medical Faculty of Meram, Necmettin Erbakan University, Konya, Turkey

    Ayhan Bilgic

Authors
  1. Selcuk Uzuner
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  2. Sezgin Sahin
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  3. Gizem Durcan
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  4. Amra Adrovic
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  8. Kayhan Bahali
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  9. Ozgur Kasapcopur
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Corresponding author

Correspondence to Kayhan Bahali.

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The study was reviewed and approved by the local ethical committee.

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We have no funding sources that supported our work.

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Uzuner, S., Sahin, S., Durcan, G. et al. The impact of peer victimization and psychological symptoms on quality of life in children and adolescents with systemic lupus erythematosus. Clin Rheumatol 36, 1297–1304 (2017). https://doi.org/10.1007/s10067-017-3650-5

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  • DOI: https://doi.org/10.1007/s10067-017-3650-5

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