Abstract
Psoriatic arthritis (PsA) is a psoriasis-associated inflammatory arthritis which causes joint destruction. There are some epidemiologic data about PsA; however, there are no sufficient data from Turkey. Herein, we evaluated the frequency of PsA in the Thrace region of Turkey according to hospital-based data. In addition, we evaluated clinical features and types of joint involvement in PsA patients. We included 172 PsA patients fulfilling CASPAR criteria admitted to the Division of Rheumatology, Trakya University Medical Faculty, between 2003 and 2012. Data from Turkish Statistical Institution was used to calculate the incidence and prevalence of PsA. Patients’ demographic features, durations of psoriasis and PsA, number of tender and swollen joints, treatment modalities, laboratory data, and X-ray film findings were recorded from hospital files. The annual incidence of PsA was 2.8/100,000. The mean annual incidence was 3.47/100,000 in females and 2.15/100,000 in males. The overall prevalence of PsA in our region was 27.9/100,000 (95 % confidence interval (CI) 23.7–32.1) in individuals >16 years. The prevalence of PsA was higher in females than in males (34.7/100,000 vs. 21.5/100,000). Polyarthritis was present in 67 (38.9 %), oligoarthritis in 47 (27.3 %), spondyloarthritis in 39 (22.6 %), and distal interphalangeal (DIP) arthritis in 19 (11.0 %) patients. The duration of psoriasis was significantly longer in polyarticular PsA patients than in DIP and oligoarticular groups (p values = 0.016 and 0.018, respectively). The number of swollen joints correlated with age (r = 0.21, p = 0.006), duration of psoriasis (r = 0.20, p = 0.01), number of tender joints (r = 0.92, p ≤ 0.001), ESR (r = 0.24, p = 0.001), and CRP (r = 0.17, p = 0.026). The frequency of PsA in Thrace region is similar to that in low-frequency regions. The most frequent type of involvement was polyarticular, and it correlated with the duration of psoriasis and erosive disease.
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Duarte GV, Faillace C, Freire de Carvalho J (2012) Psoriatic arthritis. Best Pract Res Clin Rheumatol 26:147–156
Cantini F, Niccoli L, Nannini C, Kaloudi O, Bertoni M, Cassarà E (2010) Psoriatic arthritis: a systematic review. Int J Rheum Dis 13:300–317
Sadek HA, Abdel-Nasser AM, El-Amawy TA, Hassan SZ (2007) Rheumatic manifestations of psoriasis. Clin Rheumatol 26:488–498
Prey S, Paul C, Bronsard V, Puzenat E, Gourraud PA, Aractingi S et al (2010) Assessment of risk of psoriatic arthritis in patients with plaque psoriasis: a systematic review of the literature. J Eur Acad Dermatol Venereol 24(Suppl 2):31–35
Onumah N, Kircik LH (2012) Psoriasis and its comorbidities. J Drugs Dermatol 11(5 Suppl):s5–s10
Alamanos Y, Voulgari PV, Drosos AA (2008) Incidence and prevalence of psoriatic arthritis: a systematic review. J Rheumatol 35:1354–1358
Salvarani C, Lo Scocco G, Macchioni P, Cremonesi T, Rossi F, Mantovani W et al (1995) Prevalence of psoriatic arthritis in Italian psoriatic patients. J Rheumatol 22:1499–1503
Salvarani C, Olivieri I, Cantini F, Macchioni L, Boiardi L (1998) Psoriatic arthritis. Curr Opin Rheumatol 10:299–305
Kaipiaine S (1996) Incidence of psoriatic arthritis in Finland. Br J Rheumatol 35:1289–1291
Mathieu A, Cauli A, Vacca A, Mameli A, Passiu G, Porru G et al (2007) Genetics of psoriasis and psoriatic arthritis. Reumatismo 59(Suppl 1):25–27
Creamer D, Jaggar R, Allen M, Bicknell R, Barker J (1997) Overexpression of the angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase in psoriatic epidermis. Br J Dermatol 137:851–855
Cakir N, Pamuk ON, Dervis E, Imeryüz N, Uslu H, Benian Ö et al (2012) The prevalences of some rheumatic diseases in western Turkey: Havsa study. Rheumatol Int 32:895–908
Taylor W, Gladman D, Helliwell P, Marchesoni A, Mease P, Mielants H et al (2006) Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum 54:2665–2673
Ogdie A, Langan S, Love T, Haynes K, Shin D, Seminara N et al (2013) Prevalence and treatment patterns of psoriatic arthritis in the UK. Rheumatology (Oxford) 52:568–575
Silman AJ (2001) Psoriatic arthropathy. In: Silman AJ, Hochberg MC (eds) Epidemiology of the rheumatic diseases, 2nd edn, pp 85–99
Taylor WJ (2002) Epidemiology of psoriatic arthritis. Curr Opin Rheumatol 14:98–103
Madland TM, Apalset EM, Johannesen AE, Rossebo B, Brun JG (2005) Prevalence, disease manifestations, and treatment of psoriatic arthritis in Western Norway. J Rheumatol 32:1918–1922
Alamanos Y, Papadopoulos NK, Voulgari PV, Siozos C, Psychos DN, Tympanidou M et al (2003) Epidemiology of psoriatic arthritis in Northwest Greece, 1982–2001. J Rheumatol 30:2641–2644
Reveille JD (2011) Epidemiology of spondyloarthritis in North America. Am J Med Sci 341:284–286
Gunal EK, Kamali S, Gul A, Ocal L, Konice M, Aral O et al (2009) Clinical evaluation and comparison of different criteria for classification in Turkish patients with psoriatic arthritis. Rheumatol Int 29:365–370
Nossent JC, Gran JT (2009) Epidemiological and clinical characteristics of psoriatic arthritis in Northern Norway. Scand J Rheumatol 38:251–255
Soriano ER, Rosa J, Velozo E, Schpilberg M, Imamura PM, Diaz J et al (2011) Incidence and prevalence of psoriatic arthritis in Buenos Aires, Argentina: a 6-year health management organization-based study. Rheumatology (Oxford) 50:729–734
Maejima H, Taniguchi T, Watarai A, Aki R, Katsuoka K (2010) Analysis of clinical, radiological and laboratory variables in psoriatic arthritis with 25 Japanese patients. J Dermatol 37:647–656
Gladman DD, Shuckett R, Russell ML, Thorne JC, Schachter RK (1987) Psoriatic arthritis (PSA)—an analysis of 220 patients. Q J Med 62:127–141
Inanc N, Dalkilic E, Kamali S, Kasapoglu-Günal E, Elbir Y, Direskeneli H et al (2007) Anti-CCP antibodies in rheumatoid arthritis and psoriatic arthritis. Clin Rheumatol 26:17–23
McGonagle D, Gibbon W, Emery P (1998) Classification of inflammatory arthritis by enthesitis. Lancet 352:1137–1140
Chandran V, Schentag CT, Gladman DD (2007) Sensitivity of the classification of psoriatic arthritis criteria in early psoriatic arthritis. Arthritis Rheum 57:1560–1563
Helliwell PS, Porter G, Taylor WJ (2007) Polyarticular psoriatic arthritis is more like oligoarticular psoriatic arthritis, than rheumatoid arthritis. Ann Rheum Dis 66:113–117
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Dönmez, S., Pamuk, Ö.N., Akker, M. et al. Clinical features and types of articular involvement in patients with psoriatic arthritis. Clin Rheumatol 34, 1091–1096 (2015). https://doi.org/10.1007/s10067-014-2746-4
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DOI: https://doi.org/10.1007/s10067-014-2746-4