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Lymphopenia relating to T-lymphocyte apoptosis in systemic lupus erythematosus

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References

  1. Rastin M, Hatef MR, Tabasi N, Mahmoudi M (2011) The pathway of estradiol-induced apoptosis in patients with systemic lupus erythematosus. Clin Rheumatol, Aug 12 [Epub ahead of print]

  2. Dhir V, Singh AP, Aggarwal A, Naik S, Misra R (2009) Increased T-lymphocyte apoptosis in lupus correlates with disease activity and may be responsible for reduced T-cell frequency: a cross-sectional and longitudinal study. Lupus 18:785–791

    Article  PubMed  CAS  Google Scholar 

  3. Shah D, Aggarwal A, Bhatnagar A, Kiran R, Wanchu A (2011) Association between T lymphocyte sub-sets apoptosis and peripheral blood mononuclear cells oxidative stress in systemic lupus erythematosus. Free Radic Res 45:559–567

    Article  PubMed  CAS  Google Scholar 

  4. Kaneko H, Saito K, Hashimoto H, Yagita H, Okumura K, Azuma M (1996) Preferential elimination of CD28+ T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis. Clin Exp Immunol 106:218–229

    Article  PubMed  CAS  Google Scholar 

  5. Vilá LM, Alarcón GS, McGwin G Jr et al (2006) Systemic lupus erythematosus in a multiethnic US cohort: XXXVII. Association of lymphopenia with clinical manifestations, serologic abnormalities, disease activity, and damage accrual. Arthritis Rheum 55:799–806

    Article  PubMed  Google Scholar 

  6. Budd RC, Yeh WC, Tschopp J (2006) cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol 6:196–204

    Article  PubMed  CAS  Google Scholar 

  7. Xu L, Zhang L, Yi Y, Kang HK, Datta SK (2004) Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat Med 10:411–415

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Rheumatology, First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, Hangzhou, 310003, Zhejiang Province, China

    Weiqian Chen & Jin Lin

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  1. Weiqian Chen
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  2. Jin Lin
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Correspondence to Jin Lin.

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Chen, W., Lin, J. Lymphopenia relating to T-lymphocyte apoptosis in systemic lupus erythematosus. Clin Rheumatol 30, 1515–1516 (2011). https://doi.org/10.1007/s10067-011-1852-9

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