Skip to main content

Advertisement

Log in

An unusual case of autoimmune hepatitis in a patient with adult-onset Still’s disease

  • Case Report
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Adult-onset Still's disease (AOSD) is an autoimmune disease characterized by spiking fever, evanescent rash, arthritis, serositis, and liver involvement. Although autoimmune hepatitis (AIH) has been reported in association with various autoimmune diseases, AOSD-associated AIH is rare. We herein report an unusual case of AIH in a patient with AOSD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H (1992) Preliminary criteria for classification of adult Still’s disease. J Rheumatol 19:424–430

    CAS  PubMed  Google Scholar 

  2. Khaled A, Fazaa B, Mrabet N, Zeglaoui F, Kamoun MR (2008) Multiple autoimmune syndrome in a patient with pemphigus vulgaris: a new combination. Tunis Med 86:595–597

    PubMed  Google Scholar 

  3. Gurudu SR, Mittal SK, Shaber M, Gamboa E, Michael S, Sigal LH (2000) Autoimmune hepatitis associated with autoimmune hemolytic anemia and anticardiolipin antibody syndrome. Dig Dis Sci 45:1878–1880

    Article  CAS  PubMed  Google Scholar 

  4. Marie I, Levesque H, Tranvouez JL, Francois A, Riachi G, Cailleux N, Courtois H (2001) Autoimmune hepatitis and systemic sclerosis: a new overlap syndrome? Rheumatology 40:102–106

    Article  CAS  PubMed  Google Scholar 

  5. Maclachlan D, Tyndall A (2000) Acute hepatitis in adult Still's disease apparently resulting from oral iron substitution-a case report. Clin Rheumatol 19:222–225

    Article  CAS  PubMed  Google Scholar 

  6. Jung JH, Jun JB, Yoo DH, Kim TH, Jung SS, Lee IH, Bae SC, Kim SY (2000) High toxicity of sulfasalazine in adult-onset Still's disease. Clin Exp Rheumatol 18:245–248

    CAS  PubMed  Google Scholar 

  7. Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK, Cancado EL, Chapman RW, Cooksley WG, Czaja AJ, Desmet VJ, Donaldson PT, Eddleston AL, Fainboim L, Heathcote J, Homberg JC, Hoofnagle JH, Kakumu S, Krawitt EL, Mackay IR, MacSween RN, Maddrey WC, Manns MP, McFarlane IG, Meyer zum Buschenfelde KH, Zeniya M (1999) International autoimmune hepatitis group report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 31:929–938

    Article  CAS  PubMed  Google Scholar 

  8. Kessler WR, Cummings OW, Eckert G, Chalasani N, Lumeng L, Kwo PY (2004) Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis. Clin Gastroenterol Hepatol 2:625–631

    Article  PubMed  Google Scholar 

  9. Min JK, Han NI, Kim JA, Lee YS, Cho CS, Kim HY (2001) A case of cholestatic autoimmune hepatitis and acute liver failure: an unusual hepatic manifestation of mixed connective tissue disease and Sjogren’s syndrome. J Korean Med Sci 16:512–515

    CAS  PubMed  Google Scholar 

  10. Redondo-Cerezo E, Nogueras-Lopez F, Martin-Vivaldi R, Simon EE (2002) Fulminant hepatic failure as the presenting form of type 1 autoimmune hepatitis in the elderly. Am J Gastroenterol 97:1265–1266

    Article  PubMed  Google Scholar 

  11. Kawai K, Michitaka K, Miyauchi S, Sano M, Abe M, Ninomiya T, Matsuura B, Masumoto T, Akbar SM, Horiike N, Onji M (2003) Acute-onset autoimmune hepatitis treated with living donor-liver transplantation. Intern Med 42:158–162

    Article  PubMed  Google Scholar 

  12. Ostapowicz G, Fontana RJ, Schiødt FV, Larson A, Davern TJ, Han SH, McCashland TM, Shakil AO, Hay JE, Hynan L, Crippin JS, Blei AT, Samuel G, Reisch J, Lee WM, US Acute Liver Failure Study Group (2002) Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 137:947–954

    PubMed  Google Scholar 

Download references

Acknowledgement

This work was supported in part by a grant from the Education Department of Liaoning Province, China (no. 20060917), the Program for Innovative Research Team in University (IRT0760) from the Ministry of Education of China.

Disclosures

None

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ting Xiao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Xia, LX., Xiao, T. An unusual case of autoimmune hepatitis in a patient with adult-onset Still’s disease. Clin Rheumatol 29, 95–97 (2010). https://doi.org/10.1007/s10067-009-1186-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-009-1186-z

Keywords

Navigation