Abstract
Erythema nodosum and aseptic arthritis are recognized associations of rickettsial infections. However, they usually present with a febrile illness rather than with severe arthritis. We report three patients who presented with incapacitating major joint arthritis and one who presented with severe spondyloarthropathy in addition to major joint arthritis due to serologically confirmed Orientia tsutsugamushi and Rickettsia conorii infections. All of them had erythema nodosum and low-grade fever. They had rapid clinical response to doxycycline.
Similar content being viewed by others
References
Nácher JJ, Ibáñez VN, García AN, Lleti MS, Tuset CF, Febrer I (1991) Rickettsia conorii: a new cause of erythema nodosum. Med Interna 8:241–242
Pedro-Botet J, Auguet T, Pallás O, Gimeno JL (1991) Arthritis in Mediterranean spotted fever. Infection 19:346–347
Sundy JS, Allen NB, Sexton DJ (1996) Rocky Mountain spotted fever presenting with acute monarticular arthritis. Arthritis Rheum 39:175–176
Premaratna R, Loftis AD, Chandrasena TG, Dasch GA, de Silva HJ (2008) Rickettsial infections and their clinical presentations in the Western Province of Sri Lanka: a hospital-based study. Int J Infect Dis 12:198–202 Epub 2007 Sep 27
Kularatne SAM, Edirisingha JS, Gawarammana IB, Urakami H, Chenchittikul M, Kaiho I (2003) Emerging rickettsial infections in Sri Lanka: the pattern in the hilly Central Province. Trop Med Int Health 8:803–811
Premaratna R, Chandrasena TGAN, Dassayake AS, Loftis AD, Dasch GA, de Silva HJ (2006) Acute hearing loss due to scrub typhus: a forgotten complication of a reemerging disease. Clin Infect Dis 42:e6–e8
Disclosures
None
Author information
Authors and Affiliations
Corresponding author
Additional information
The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the United States Department of Health and Human Services or the Centers for Disease Control and Prevention.
Rights and permissions
About this article
Cite this article
Premaratna, R., Chandrasena, T.G.A.N., Rajapakse, R.P.V.J. et al. Rickettsioses presenting as major joint arthritis and erythema nodosum: description of four patients. Clin Rheumatol 28, 867–868 (2009). https://doi.org/10.1007/s10067-009-1166-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10067-009-1166-3