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The dynamism of cutaneous lupus erythematosus: mild discoid lupus erythematosus evolving into SLE with SCLE and treatment-resistant lupus panniculitis

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Abstract

We present a 47-year-old Caucasian female who initially presented with mild discoid lupus erythematosus that evolved into systemic lupus erythematosus with subacute cutaneous LE and treatment-recalcitrant lupus panniculitis. Conventional therapy with antimalarials, systemic steroids, azathioprine, cyclophosphamide, methotrexate, and pulse doses of methylprednisolone did not control the course of the disease. Cyclosporin-A treatment led to clinical improvement and maintained remission.

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Acknowledgement

This work has been supported by grant from Medical University of Lodz, no. 503-119-1.

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Authors and Affiliations

  1. Department of Dermatology, Medical University of Lodz, Lodz, Poland

    Anna Wozniacka, Małgorzata Salamon, Aleksandra Lesiak & Anna Sysa-Jedrzejowska

  2. Rutland Medical Center, Rutland, VT, USA

    Daniel Paul McCauliffe

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  1. Anna Wozniacka
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  2. Małgorzata Salamon
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  3. Aleksandra Lesiak
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  4. Daniel Paul McCauliffe
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  5. Anna Sysa-Jedrzejowska
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Correspondence to Anna Wozniacka.

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Wozniacka, A., Salamon, M., Lesiak, A. et al. The dynamism of cutaneous lupus erythematosus: mild discoid lupus erythematosus evolving into SLE with SCLE and treatment-resistant lupus panniculitis. Clin Rheumatol 26, 1176–1179 (2007). https://doi.org/10.1007/s10067-006-0310-6

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  • DOI: https://doi.org/10.1007/s10067-006-0310-6

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