Skip to main content
Log in

Severe gastrointestinal involvement in systemic sclerosis

  • Case Report
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Gastrointestinal tract (GIT) is the most common organ system involved in systemic sclerosis (SSc). GIT involvement is mainly attributed to GIT dismobility and wide mouth diverticular. GIT involvement in SSc can be also severely debilitating and even life threatening. To our knowledge, the presence of gastrointestinal bleeding due to the presence of multiple peptic ulcers in scleroderma patients is not well described. In this case report, we describe a scleroderma patient with recurrent gastrointestinal bleeding due to multiple peptic ulcers, in which vagotomy, pyloroplasty, and cholocystectomy were performed and subcutaneous somatostatin was administered to discontinue the recurrent bleeding and stabilize her clinical condition.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Jaovisidha Kanyakorn, Csuka ME, Almagro Urias, Soergel Konrad (2005) Severe gastrointestinal involvement in systemic sclerosis: report of five cases and review of the literature. Semin Arthritis Rheum 34:689–702 (Feb)

    Article  PubMed  Google Scholar 

  2. Valle JD, Scheiman JM (1999) Zollinger–Ellison syndrome. In: Yamada T, Alpers DH, Laine L, Owyang C, Powell DW (eds) Textbook of Gastroenterology, 3rd edn. Williams & Wilkins, Philadelphia, pp 1445–1462

    Google Scholar 

  3. Frucht H, Howard JM, Slaff JI et al (1989) Secretin and calcium provocative tests in the Zollinger–Ellison syndrome. Ann Intern Med 111:713–722

    PubMed  CAS  Google Scholar 

  4. McGuigan JE, Wolfe MM (1980) Secretin injection test in the diagnosis of gastrinoma. Gastroenterology 81:758–762

    Google Scholar 

  5. Mignon M, Rigaud D, Cambray S et al (1985) A comparative evaluation of secretin bolus and secretin infusion as secretin provocation tests in the Zollinger–Ellison syndrome. Scand J Gastroenterol 20:791–797

    PubMed  CAS  Google Scholar 

  6. Matsui T, Iida M, Nanbu T et al (1985) A study of secretin dosage of secretin provocation test in the Zollinger–Ellison syndrome. Nippon Shokakibyo Gakkai Zasshi [Jpn J Gastroenterol] 82:288–295

    CAS  Google Scholar 

  7. Yamamoto C, Aoyagi K, Iwata K, Morita I, Hotokezaka M, Funakoshi S, Sakamoto K, Iida M, Sakisaka S (2005) Double doses of secretin contribute to diagnosis of Zollinger–Ellison syndrome in secretin and selective arterial secretion injection tests—a case report. Dig Dis Sci 50:2034–2036 (Nov)

    Article  PubMed  Google Scholar 

  8. Medsger TA Jr (2001) Systemic sclerosis (Scleroderma): clinical aspects. In: Koopman WJ (ed) Arthritis and allied conditions. Williams & Wilkins, Philadelphia, PA, pp 1590–1624

    Google Scholar 

  9. Steen VD, Medsger TA Jr (2000) Severe organ involvement in systemic sclerosis with diffuse scleroderma. Arthritis Rheum 43:2437–2444

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

All of the authors participated in the writing of the manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sotiris C. Plastiras.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Plastiras, S.C., Tzivras, M. & Vlachoyiannopoulos, P.G. Severe gastrointestinal involvement in systemic sclerosis. Clin Rheumatol 26, 1025–1026 (2007). https://doi.org/10.1007/s10067-006-0264-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-006-0264-8

Keywords

Navigation