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Systemic lupus erythematosus in a patient with human immunodeficiency virus infection – challenges in diagnosis and management

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Abstract

Systemic lupus erythematosus (SLE) is mainly a disease of young women. The problem of coexistent human immunodeficiency virus (HIV) infection is a growing problem in sub-Saharan Africa. We describe a case of active life-threatening neuropsychiatric lupus in a patient with underlying HIV infection. The challenges of interpreting physical signs and laboratory features that are common to both conditions, and the dilemma of treating active SLE with cytotoxics in the immunocompromised patient, are discussed.

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Abbreviations

AIDS:

Acquired immunodeficiency syndrome

ART:

antiretroviral therapy

DLE:

discoid lupus erythematosus

HIV:

Human immunodeficiency virus

SLE:

systemic lupus erythematosus

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Correspondence to T. Gould.

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Gould, T., Tikly, M. Systemic lupus erythematosus in a patient with human immunodeficiency virus infection – challenges in diagnosis and management. Clin Rheumatol 23, 166–169 (2004). https://doi.org/10.1007/s10067-003-0833-z

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  • DOI: https://doi.org/10.1007/s10067-003-0833-z

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