Abstract
Near infrared topographic imaging is a novel non-invasive technique to obtain the activated region in the brain cortex. The light propagation in the head is strongly scattered and this causes results in poor spatial resolution and contrast in the topographic images. Adequate modelling of light propagation in the head in order to deduce the volume of tissue interrogated by a source-detector pair for topographic imaging is very important to improve the quality of image of brain activity. In this study, the light propagation in a three-dimensional realistic head model is calculated by the finite difference method. The geometry of the model is generated from axial slices of an MRI scan. The topographic image is obtained from the change in intensity detected by source-detector pairs caused by the brain activity. The images obtained by two types of source-detector arrangement are compared to evaluate the efficiency of source-detector arrangement. The results show that the double-density arrangement improves the quality of the topographic image of the brain activity.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
S. J. Matcher, C. E. Elwell, C. E. Cooper, M. Cope and D. T. Delpy: Anal. Biochem. 227 (1995) 54.
G. Gratton, M. Fabiani, D. Friedman, M. A. Franceschini, S. Fantini, P. Corballis and E. Gratton: J. Cognitive Neurosci. 7 (1995) 446.
S. Kohri, Y. Hoshi, M. Tamura, C. Kato, Y. Kuge and N. Tamaki: Physiol. Meas. 23 (2002) 301.
M. Niwayama, L. Lin, J. Shao, N. Kudo and K. Yamamoto: Rev. Sci. Instrum. 71 (2000) 4571.
A. Maki, Y. Yamashita, Y. Ito, E. Watanabe, Y. Mayanagi and H. Koizumi: Med. Phys. 22 (1995) 1997.
H. Koizumi, Y. Yamashita, A. Maki, T. Yamamoto, Y. Ito, H. Itagaki and R. Kennan: J. Biomed. Opt. 4 (1999) 403.
D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota and J. B. Mandeville: Neuroimage 13 (2001) 76.
T. Yamamoto, A. Maki, T. Kadoya, Y. Tanikawa, Y. Yamada, E. Okada and H. Koizumi: Phys. Med. Biol. 47 (2002) 3429.
M. Firbank, E. Okada and D. T. Delpy: Neuroimage 8 (1998) 69.
D. A. Boas, J. P. Culver, J. J. Stott and A. K. Dunn: Opt. Express 10 (2002) 159.
C. R. Simpson, M. Kohl, M. Essenpreis and M. Cope: Phys. Med. Biol. 43 (1998) 2465.
M. Firbank, M. Hiraoka, M. Essenpreis and D. T. Delpy: Phys. Med. Biol. 38 (1993) 503.
P. van der Zee, M. Essenpreis and D. T. Delpy: Proc. SPIE 1888 (1993) 454.
M. S. Patterson, S. J. Madsen, J. D. Moulton and B. C. Wilson: IEEE Microwave Theory and Techniques Symp. Digest, 1991, p. 905.
S. R. Arridge, M. Schweiger, M. Hiraoka and D. T. Delpy: Med. Phys. 20 (1993) 299.
B. W. Pogue, M. S. Patterson, H. Jiang and K. D. Paulsen: Phys. Med. Biol. 40 (1995) 1709.
Numerical Analysis of Heat and Flow (Corona Publish C., L, Tokyo, 1986) [in Japanese].
W. H. Pres, S. A. Teukolsky, W. T. Vetterling and B. P. Flannery: Numerical Recipes in Fortran (Cambridge University Press: New York, 1992) 2nd ed. p. 816.
E. Okada, M. Firbank, M. Schweiger, S. R. Arridge, M. Cope and D. T. Delpy: Appl. Opt. 36 (1997) 21.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fukui, Y., Yamamoto, T., Kato, T. et al. Analysis of Light Propagation in a Three-Dimensional Realistic Head Model for Topographic Imaging by Finite Difference Method. OPT REV 10, 470–473 (2003). https://doi.org/10.1007/s10043-003-0470-4
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s10043-003-0470-4