Skip to main content

Advertisement

Log in

Nanosecond Time-Gated Spectroscopy of Laser-Ablation Plume of Human Hair to Detect Calcium for Potential Diagnoses

  • ENVIRONMENTAL, BIOLOGICAL, AND SPACE OPTICS
  • Published:
Optical Review Aims and scope Submit manuscript

Abstract

We demonstrate the nanosecond time-gated spectroscopy of plume luminescence in UV laser ablation of human hair. Clear and sharp peaks of calcium ion (Ca+) appear in the spectrum although the Ca content is only 0.1% in human hair. Highly sensitive detection of Ca is thus possible. In the experiment, the peak intensity of Ca+ was measured for human hair samples of female subjects over a wide range of age, and compared to the bone mineral density of the lumbar vertebrae of the subjects themselves. Our experimental results suggest that this specific spectroscopy has the potential for novel diagnoses including monitoring of daily Ca intake and a screening diagnosis of osteoporosis. The spectroscopic system and time transition of plume-luminescence spectra are also described.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. S. L. Trokel, R. Srinivasan and B. Braren: Am. J. Opthalmol. 96 (1983) 710.

    Google Scholar 

  2. C. A. Puliafito, R. F. Steinert, T. F. Deutsch, F. Hillenkamp, E. J. Dehm and C. M. Adler: Opthalmol. 92 (1985) 741.

    Google Scholar 

  3. J. M. Isner, P. G. Steg and R. H. Clarke: IEEE J. Quantum Electron. 23 (1987) 1756.

    Article  Google Scholar 

  4. C. A. Puliafito, D. Stern, R. R. Krueger and E. R. Mandel: Arch. Ophthalmol. 105 (1987) 1255.

    PubMed  Google Scholar 

  5. K. T. Schomacker, Y. Domankevitz, T. J. Flotte and T. F. Deutsch: Laser Surg. Med. 11 (1991) 141.

    Google Scholar 

  6. S. Fujisaka, T. Ito and K. Sato: Rev. Laser Eng. 22 (1994) 552 (in Japanese).

    Google Scholar 

  7. Y. Shimaoka, M. Nakamura, M. Ohmi and M. Haruna: Proc. of the Pacific Rim Conf. Lasers & Electro-Optics (CLEO/PR), Makuhari, Chiba, Japan, 1997, p. 261.

  8. S. Andersson-Engels, J. Johansson and S. Svanberg: Anal. Chem. 61 (1989) 1367.

    Google Scholar 

  9. P. Teng, N. S. Nishioka, R. R. Anderson and T. F. Deutsch: Appl. Phys. B 42 (1987) 73.

    Article  Google Scholar 

  10. L. I. Deckelbaum, J. J. Scott, M. L. Stetz, K. M. O’Brien and G. Baker: Lasers Surg. Med. 12 (1992) 18.

    PubMed  Google Scholar 

  11. A. A. Oraevsky, S. L. Jacques, G. H. Pettit, F. K. Tittel and P. D. Henry: Lasers Surg. Med. 13 (1993) 168.

    PubMed  Google Scholar 

  12. B. Zysset, J. G. Fujimoto, C. A. Puliafito, R. Birngruber and T. F. Deutsch: Lasers Surg. Med. 9 (1989) 193.

    PubMed  Google Scholar 

  13. R. O. Esenaliev, A. A. Oraevsky and V. S. Letokhov: IEEE Trans. Biomed. Eng. 36 (1989) 1188.

    Article  PubMed  Google Scholar 

  14. H. Orimo, Y. Sugioka, I. Itsuki, T. Nakamua, H. Fukunaga, T. Hotokefuchi and Y. Muto: Osteoporosis Jpn. 3 (1995) 111 (in Japanese).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masato Ohmi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ohmi, M., Nakamura, M., Morimoto, S. et al. Nanosecond Time-Gated Spectroscopy of Laser-Ablation Plume of Human Hair to Detect Calcium for Potential Diagnoses. OPT REV 7, 353–357 (2000). https://doi.org/10.1007/s10043-000-0353-x

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10043-000-0353-x

Key words

Navigation