Skip to main content

Advertisement

Log in

Laparoscopic intraperitoneal onlay mesh (IPOM) repair using n-butyl-2-cyanoacrylate (Liquiband Fix8™) for mesh fixation: learning experience and short-medium term results

  • How-I-Do-It
  • Published:
Hernia Aims and scope Submit manuscript

Abstract

Aim

The purpose of this study was to evaluate a novel hernia repair glue fixation device (LiquibandFix8™) in laparoscopic IPOM repair for incisional hernias.

Methods

All ventral incisional hernia patients requiring laparoscopic IPOM repair were included in the study. A retrospective review of the data was performed.

Results

137 patients underwent 138 laparoscopic IPOM repairs for incisional hernias using n-butyl-2-cyanoacrylate (LiquibandFix8™) for mesh fixation over a 40-month period by a single experienced laparoscopic surgeon. There were 70 males and 67 females, median age 54 years (range 23–80 years). Defects were predominantly midline n = 123/138 (89%) and were closed by transfascial sutures in 126/138 (91%) prior to IPOM repair (IPOM plus). Mesh fixation was successful in all 138 repairs. Synthetic meshes (Symbotex™ [polyester/collagen composite, Medtronic] n = 80, and Dynamesh® [polypropylene/PVDF composite, FEG Textiltechnik mbH] n = 5) and biologic meshes (Surgimend® [bovine collagen dermal matrix, Integra] n = 53) were used. Median follow-up was 32 months (range 12–48 months). There were 16 adverse events in 12 patients (9%): conversion to open surgery (inadvertent enterotomy) 2 (1.5%), bladder perforation 1, intraperitoneal bleeding 2, port-site haematoma 2, port site wound infection 1, post-op ileus 2, chest infection 1, seroma 1 (1%), hernia recurrence 3 (2%) and chronic pain 2 (1.5%).

Conclusion

This retrospective study shows that mesh fixation in laparoscopic IPOM using cyanoacrylate glue with the Liquiband Fix8™ device is feasible, safe, easy to learn, and is associated with a low risk of seroma, hernia recurrence and chronic pain with short-medium term follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Pierce RA, Spitler JA, Frisella MM, Brunt LM (2007) Pooled data analysis of laparoscopic vs. open ventral hernia repair: 14 years of patient data accrual. Surg Endosc 21:378

    Article  Google Scholar 

  2. Suwa K, Okamoto T, Yanaga K (2016) Closure versus non-closure of fascial defects in laparoscopic ventral and incisional hernia repairs: a review of the literature. Surg Today 46(7):764–773

    Article  Google Scholar 

  3. Reynvoet E, Deschepper E, Rogiers X, Troisi R, Berrevoet F (2014) Laparoscopic ventral hernia repair: is there an optimal mesh fixation technique? A systematic review. Langenbecks Arch Surg 399(1):55–63

    Article  Google Scholar 

  4. Bansal VK, Asuri K, Panaiyadiyan S, Subramanian R, Ramachandran R, Sagar R, Misra MC (2016) Comparison of absorbable versus nonabsorbable tackers in terms of long-term outcomes, chronic pain, and quality of life after laparoscopic incisional hernia repair: a randomized study. Surg Laparosc Endosc Percutaneous Tech 26(6):476–483

    Article  Google Scholar 

  5. Golash V (2008) Large gut fistula due to a protruding spiral tacker after laparoscopic repair of a ventral hernia. Oman Med J 23:50–52

    PubMed  PubMed Central  Google Scholar 

  6. Ladurner R, Mussack T (2004) Small bowel perforation due to protruding spiral tackers: a rare complication in laparoscopic incisional hernia repair. Surg Endosc 18:1001

    CAS  PubMed  Google Scholar 

  7. Kockerling F, Shug-Pass C, Bittner R (2018) A word of caution: never use tacks for mesh fixation to the diaphragm! Surg Endosc 32:3295–3302

    Article  CAS  Google Scholar 

  8. Petter-Puchner AH, Fortelny R, Mittermayr R et al (2005) Fibrin sealing versus stapling of hernia meshes in an onlay model in the rat. Hernia 9:322–329

    Article  Google Scholar 

  9. Eriksen JR, Bech JI, Linnemann D et al (2008) Laparoscopic intraperitoneal mesh fixation with fibrin sealant (Tisseel) vs. titanium tacks: a randomised controlled experimental study in pigs. Hernia 12:483–491

    Article  CAS  Google Scholar 

  10. Clarke T, Katkhouda N, Mason RJ et al (2011) Fibrin glue for intraperitoneal laparoscopic mesh fixation: a comparative study in a swine model. Surg Endosc 25:737–748

    Article  Google Scholar 

  11. Olmi S, Scaini A, Erba L et al (2007) Use of fibrin glue (Tissucol) in laparoscopic repair of abdominal wall defects: preliminary experience. Surg Endosc 21:409–413

    Article  CAS  Google Scholar 

  12. Olmi S, Cesana G, Sagutti L et al (2010) Laparoscopic incisional hernia repair with fibrin glue in select patients. JSLS 14:240–245

    Article  Google Scholar 

  13. Eriksen JR, Bisgaard T, Assaadzadeh S et al (2011) Randomized clinical trial of fibrin sealant versus titanium tacks for mesh fixation in laparoscopic umbilical hernia repair. Br J Surg 98:1537–1545

    Article  CAS  Google Scholar 

  14. Dilege E, Deveci U, Erbil Y et al (2010) N-butyl cyanoacrylate versus conventional suturing for fixation of meshes in an incisional hernia model. J Invest Surg 23:262–266

    Article  Google Scholar 

  15. Losi P, Burchielli S, Spiller D et al (2010) Cyanoacrylate surgical glue as an alternative to suture threads for mesh fixation in hernia repair. J Surg Res 163:53–58

    Article  Google Scholar 

  16. Kull S, Martinelli I, Briganti E et al (2009) Glubran2 surgical glue: in vitro evaluation of adhesive and mechanical properties. J Surg Res 157:15–21

    Article  Google Scholar 

  17. Kukleta JF, Freytag C, Weber M (2012) Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1300 mesh fixations. Hernia 16:153–162

    Article  CAS  Google Scholar 

  18. Burza A, Avantifiori R, Curinga R, Santini E, Delle Site P, Stipa F (2014) Comparison between two different mesh fixation methods in laparoscopic inguinal hernia repair: tacker vs. Synthetic cyanoacrylate glue. Minerva Chir 69(6):321–329

    CAS  PubMed  Google Scholar 

  19. Krikunov D, Akimov V, Toidze V, Churgulia M, Dvaladze L (2018) Comparative evaluation of TAPP hernioplasty with use of various methods of fixing the reticular endoprosthesis and TEP in the treatment of inguinal hernias. Georgian Med News 278:15–20

    Google Scholar 

  20. Wilson P, Hickey L (2019) Laparoscopic transabdominal preperitoneal (TAPP) groin hernia repair using n-butyl-2-cyanoacrylate (Liquiband®Fix8™) for mesh fixation and peritoneal closure. Learning experience during introduction into clinical practice. Hernia 23(3):601–613

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The author would like to thank Tina Warburton, Clinical Research Associate, Advanced Medical Solutions Group plc for her assistance with preparation of the manuscript and Irfan Qureshi, Global Senior Product Manager, Advanced Medical Solutions Group plc for his support.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to P. Wilson.

Ethics declarations

Conflict of interest

The author has received speaker honoraria and honoraria for consultation from Advanced Medical Solutions plc.

Ethical approval

All procedures performed in this study were in accordance with the ethical standards of our institution and the UK NHS Health Research Authority and with the 1964 Helsinki declaration and its later amendments.

Human and animal rights

This study did not involve the use of animals.

Informed consent

This retrospective study did not require formal consent.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wilson, P. Laparoscopic intraperitoneal onlay mesh (IPOM) repair using n-butyl-2-cyanoacrylate (Liquiband Fix8™) for mesh fixation: learning experience and short-medium term results. Hernia 24, 1387–1396 (2020). https://doi.org/10.1007/s10029-020-02144-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10029-020-02144-3

Keywords

Navigation