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Conservative management of mesh-site infection in hernia repair surgery: a case series

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Abstract

Purpose

The aim of this study is to assess the outcome of conservative management of infected mesh grafts following abdominal wall hernia repair.

Methods

This study retrospectively examined the charts of patients who developed mesh-site infection following surgery for abdominal hernia repair to determine how effective conservative management in the form of antibiotics and wound management was on the resolution of infection and wound healing.

Results

Over a period of 30 months, 13 patients developed infected mesh grafts post-hernia repair surgery. Twelve patients were successfully treated conservatively with local wound care and antibiotics if clinically indicated. One patient returned to theatre to have the infected mesh removed. Of the patients that healed eleven were treated with negative pressure wound therapy (VAC®).

Conclusion

This series of case studies indicate that conservative management of abdominal wall-infected hernia mesh cases is likely to be successful.

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References

  1. National Institute for Clinical Excellence (2008) Surgical site infection prevention and treatment of surgical site infection. NICE Clinical Guidelines, No. 74, National Collaborating Centre for Women’s and Children’s Health (UK). RCOG Press, London

  2. Smyth ET, McIlvenny G, Enstone JE et al (2008) Four country healthcare associated infection prevalence survey 2006; overview of the results. J Hosp Infect 69:230–248

    Article  CAS  PubMed  Google Scholar 

  3. Horan TC, Gaynes RP, Martone WJ et al (1992) CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13:606–608

    Article  CAS  PubMed  Google Scholar 

  4. Kingsworth A, LeBlanc K (2003) Hernias: inguinal and incisional. Lancet 362:1561–1571

    Article  Google Scholar 

  5. Saettele TM, Bachman SL, Costello CR, Grant SA, Cleveland DS, Loy TS, Kolder DG, Ramshaw BJ (2007) Use of porcine dermal collagen as a prosthetic mesh in a contaminated field for ventral hernia repair: a case report. Hernia 11(3):279–285

    Article  CAS  PubMed  Google Scholar 

  6. Kissane NA, Itani KM (2012) A decade of ventral incisional hernia repairs with biologic acellular dermal matrix: what have we learned? Plast Reconstr Surg 130(5 Suppl 2):194S–202S

    Article  CAS  PubMed  Google Scholar 

  7. Cavallaro A, Lo Menzo E, Di Vita M, Zanghì A, Cavallaro V, Veroux PF, Cappellani A (2010) Use of biological meshes for abdominal wall reconstruction in highly contaminated fields. World J Gastroenterol 16(15):1928–1933

    Article  PubMed Central  PubMed  Google Scholar 

  8. Office for National Statistics (2010) Ageing—fastest increase in the ‘Oldest Old’. ONS, London. See http://www.statistics.gov.uk/cci/nugget.asp?id=949

  9. MacFadyen BV, Mathis CR (1994) Inguinal herniorrhaphy: complications and recurrence. Semin Laparosc Surg 1:128

    PubMed  Google Scholar 

  10. Dabbas N, Adams K, Pearson K, Royle GT (2011) Frequency of abdominal wall hernias: is classical teaching out of date? J R Soc Med Short Rep 2:5

    Article  Google Scholar 

  11. Hesselink VJ, Luijendijk RW, de Wilt JH, Heide R, Jeekel J (1993) An evaluation of risk factors in incisional hernia recurrence. Surg Gynecol Obstet 176:228–234

    CAS  PubMed  Google Scholar 

  12. Luijendijk RW, Hop WC, van den Tol MP et al (2000) A comparison of suture repair with mesh repair for incisional hernia. N Engl J Med 343:392–398

    Article  CAS  PubMed  Google Scholar 

  13. Schumpelick V, Conze J, Klinge U (1996) Preperitoneal meshplasty in incisional hernia repair. A comparative retrospective study of 272 operated incisional hernias. Der Chirurg 67:1028–1035

    Google Scholar 

  14. Petersen S, Henke G, Freitag M et al (2001) Deep prosthesis infection in incisional hernia repair: predictive factors and clinical outcome. Eur J Surg 167:453–457

    Article  CAS  PubMed  Google Scholar 

  15. Jezupovs A, Mihelsons M (2006) The analysis of infection after polypropylene mesh repair of abdominal wall hernia. World J Surg 30:2270–2278

    Article  PubMed  Google Scholar 

  16. Mavros MN, Athansiou S, Alexiou VG, Mitsikostas PK, Peppas G, Falagas ME (2011) Risk factors for mesh-related infections after hernia repair surgery: a meta-analysis of cohort studies. World J Surg 35(11):2389–2398

    Article  PubMed  Google Scholar 

  17. Vrijland WW, van den Tol MP, Luijendijk RW et al (2002) Randomized clinical trial of non-mesh versus mesh repair of primary inguinal hernia. Br J Surg 89:293–297

    Article  CAS  PubMed  Google Scholar 

  18. Kercher KW, Sing RF, Matthews BD, Heniford BT (2002) Successful salvage of infected PTFE mesh after ventral hernia repair. Ostomy Wound Manage 48:40–45

    PubMed  Google Scholar 

  19. Falagas ME, Kasiakou SK (2005) Mesh-related infections after hernia repair surgery. Clin Microbiol Infect 11:3–8

    Article  CAS  PubMed  Google Scholar 

  20. Bliziotis IA, Kasiakou SK, Kapaskelis AM, Falagas ME (2006) Mesh related infection after hernia repair: case report of an emergencing type of foreign body related infection. Infection 34:46–48

    Article  CAS  PubMed  Google Scholar 

  21. Trunzo JA, Ponsky JL, Jin J et al (2009) A novel approach for salvaging infected prosthetic mesh after ventral hernia repair. Hernia 13:545–549

    Article  CAS  PubMed  Google Scholar 

  22. Delikoukos S, Tzovaras G, Liakou P et al (2007) Late onset deep mesh infection after inguinal hernia repair. Hernia 11:15–17

    Article  CAS  PubMed  Google Scholar 

  23. Stremitzer S, Bachleitner-Hofmann T, Gradl B, Gruenbeck M, Bachleitner-Hofmann B, Mittlboeck M, Bergmann M (2010) Mesh graft infection following abdominal hernia repair: risk factor evaluation and strategies of mesh graft preservation. A retrospective analysis of 476 operations. World J Surg 34(7):1702–1709

    Article  PubMed  Google Scholar 

  24. Aufenacker TJ, Koelemay MJ, Gouma DJ, Simons MP (2006) Systematic review and meta-analysis of the effectiveness of antibiotic prophylaxis in prevention of wound infection after mesh repair of abdominal wall hernia. Br J Surg 93(1):5–10

    Article  CAS  PubMed  Google Scholar 

  25. Szczerba S, Dumanian GA (2003) Definitive surgical treatment of infected or exposed ventral hernia mesh. Ann Surg 237(3):437–441

    PubMed Central  PubMed  Google Scholar 

  26. Sajjad A, Mufti TS, Zafar A, Akbar I (2007) Conservative management of mesh site infection in ventral hernia repair. J Ayub Med Coll Abbottabad 19(4):75–77

    Google Scholar 

  27. Malone DL, Genuit T, Tracy JK et al (2002) Surgical site infections: reanalysis of risk factors. J Surg Res 103:89–95

    Article  PubMed  Google Scholar 

  28. Demiter S, Gecim IE, Aydinuraz K et al (2001) Affinity of Staphylococcus epidermidis to various prosthetic graft materials. J Surg Res 99:70–74

    Article  Google Scholar 

  29. Cobb WS, Harris JB, Lokey JS, Mc Gill ES et al (2003) Incisional herniorrhaphy with intraperitoneal composite mesh: a report of 95 cases. Am Surg 69:784–787

    PubMed  Google Scholar 

  30. Arroyo A, Garcia P, Perez F et al (2001) Randomized clinical trial comparing suture and mesh repair of umbilical hernia repair in adults. Br J Surg 88:1321–1323

    Article  CAS  PubMed  Google Scholar 

  31. Adrales G (2010) Biological meshes—indications and shortcomings. Challenging hernias post-graduate course. 12th World Congress of Endoscopic Surgery

  32. Ventral Hernia Working Group, Breuing K, Butler CE, Ferzoco S et al (2010) Incisional ventral hernias: review of the literature and recommendations regarding the grading and techniques of repair. Surgery 148:544–558

    Google Scholar 

  33. Bellows CF, Smith A, Malsbury J, Helton WS (2013) Repair of incisional hernias with biological prosthesis: a systematic review of current evidence. Am J Surg 205(1):85–101

    Article  PubMed  Google Scholar 

  34. Slater NJ, van der Kolk M, Hendriks T, van Goor H, Bleichrodt RP (2013) Biologic grafts for ventral hernia repair: a systematic review. Am J Surg 205(2):220–230

    Article  PubMed  Google Scholar 

  35. Stawicki SP, Schwarz NS, Schrag SP, Lukaszczyk JJ, Schadt ME et al (2007) Application of vacuum assisted therapy in postoperative ascetic fluid leaks: an integral part of multimodality wound management in cirrhotic patients. J Burns Wounds 6:e7

    PubMed Central  PubMed  Google Scholar 

  36. Venturi ML, Attinger CE, Mesbahi AN et al (2005) Mechanisms and clinical applications of the vacuum assisted closure device: a review. Am J Clin Dermatol 6:185–194

    Article  Google Scholar 

  37. Chen SZ, Li J, Li XY, Xu LS (2005) Effects of vacuum assisted closure on wound microcirculation: an experimental study. Asian J Surg 28:211–216

    Article  PubMed  Google Scholar 

  38. Weed T, Ratcliffe C, Drake DB (2004) Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance? Ann Plast Surg 52:279–280

    Article  Google Scholar 

  39. DeFranzo AJ, Pitzer K, Molnar JA, Marks MW, Change MC, Miller PR, Letton RW, Argenta LC (2008) Vacuum-assisted closure for defects of the abdominal wall. Plastic Reconstr Surg 121(3):832–839

    Article  CAS  Google Scholar 

  40. Perez D, Wildi S, Demartines N, Bramkamp M, Koehler C, Clavien PA (2007) Prospective evaluation of vacuum-assisted closure in abdominal compartment syndrome and severe abdominal sepsis. J Am Coll Surg 205(4):586–592

    Article  PubMed  Google Scholar 

  41. Berrevoet F, Vanlander A, Sainz-Barriga M et al (2013) Infected large pore meshes may be salvaged by topical negative pressure therapy. Hernia 17:67–73

    Article  CAS  PubMed  Google Scholar 

  42. Aguilar B, Alyssa B, Chapital MD et al (2010) Conservative management of mesh site infection in hernia repair. J Laparoendosc Adv Surg Tech 20(3):249–252

    Article  Google Scholar 

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Correspondence to M. Clarke Moloney.

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Meagher, H., Clarke Moloney, M. & Grace, P.A. Conservative management of mesh-site infection in hernia repair surgery: a case series. Hernia 19, 231–237 (2015). https://doi.org/10.1007/s10029-013-1069-8

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  • DOI: https://doi.org/10.1007/s10029-013-1069-8

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