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Case of Large Placental Chorioangioma Associated with Diffuse Neonatal Hemangiomatosis

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Pediatric and Developmental Pathology

Abstract

Chorioangioma is the most frequent nontrophoblastic tumor of the placenta with a incidence ranging from 0.01 to 1.3%. Vascular anomalies of the placenta coincidental with infantile hemangioendothelioma (IH) of the liver are rarely described. Here we report a case of a large chorioangioma of the placenta associated with cutaneous hemangiomatosis and IH of the liver. The relationship between hemangiomas and placental chorioangioma is discussed.

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References

  1. Fox, H, Elston, CW (1978) “Non-trophoblastic tumors of the placenta” In: Pathology of the Placenta, WB Saunders, London, pp 343–367

  2. PF Benson MC Joseph (1961) ArticleTitleCardiomegaly in a newborn due to placental chorioangioma Br Med J 1 102–104

    Google Scholar 

  3. HC Wallenburg (1971) ArticleTitleChorioangioma of the placenta. Thirteen new cases and a review of the literature from 1939 to 1970 with special reference to the clinical complications Obstet Gynecol Surv 26 411–425 Occurrence Handle4950893

    PubMed  Google Scholar 

  4. RA Quintero H Reich R Romero MP Johnson L Goncalves MI Evans (1996) ArticleTitleIn utero endoscopic devascularization of a large chorioangioma Ultrasound Obstet Gynecol 8 48–52 Occurrence Handle10.1046/j.1469-0705.1996.08010048.x Occurrence Handle1:STN:280:ByiD3c%2FltlE%3D Occurrence Handle8843620

    Article  CAS  PubMed  Google Scholar 

  5. C Batukan W Holzgreve E Danzer E Bruder I Hosli S Tercanli (2001) ArticleTitleLarge placental chorioangioma as a cause of sudden intrauterine fetal death. A case report Fetal Diagn Ther 16 394–397 Occurrence Handle10.1159/000053946 Occurrence Handle1:STN:280:DC%2BD3MnktFGmtA%3D%3D Occurrence Handle11694744

    Article  CAS  PubMed  Google Scholar 

  6. DW Metry AA Hebert (2000) ArticleTitleBenign cutaneous vascular tumors of infancy: when to worry, what to do Arch Dermatol 136 905–914 Occurrence Handle10.1001/archderm.136.7.905 Occurrence Handle1:STN:280:DC%2BD3czkvFeisQ%3D%3D Occurrence Handle10890993

    Article  CAS  PubMed  Google Scholar 

  7. I Witters MT Van Damme P Ramaekers FA Van Assche JP Fryns (2003) ArticleTitleBenign multiple diffuse neonatal hemangiomatosis after a pregnancy complicated by polyhydramnios and a placental chorioangioma Eur J Obstet Gynecol Reprod Biol 106 83–85 Occurrence Handle10.1016/S0301-2115(02)00163-X Occurrence Handle12475589

    Article  PubMed  Google Scholar 

  8. P Goodman R Dominguez M Castillo (1992) ArticleTitleDiffuse neonatal hemangiomatosis: imaging findings in two patients Comput Med Imaging Graph 16 117–120 Occurrence Handle10.1016/0895-6111(92)90124-R Occurrence Handle1:STN:280:By2B3szjvVY%3D Occurrence Handle1568198

    Article  CAS  PubMed  Google Scholar 

  9. E Lopriore DG Markhorst (1999) ArticleTitleDiffuse neonatal haemangiomatosis: new views on diagnostic criteria and prognosis Acta Paediatr 88 93–97 Occurrence Handle10.1080/08035259950170682 Occurrence Handle1:STN:280:DyaK1M7ovV2ltw%3D%3D Occurrence Handle10090556

    Article  CAS  PubMed  Google Scholar 

  10. DJ Gersell FT Kraus (2002) Nontrophoblastic tumors RJ Kurman (Eds) Blaustein’s Pathology of the Female Genital Tract. 5th ed Springer-Verlag New York 1171–1173

    Google Scholar 

  11. AF Mesia P Mo LR Ylagan (1999) ArticleTitleAtypical cellular chorangioma Arch Pathol Lab Med 123 536–538 Occurrence Handle10383809

    PubMed  Google Scholar 

  12. AF Bree E Siegfried C Sotelo-Avila G Nahass (2001) ArticleTitleInfantile hemangiomas: speculation on placental trophoblastic origin Arch Dermatol 137 573–577 Occurrence Handle1:STN:280:DC%2BD3MzhsVKjtQ%3D%3D Occurrence Handle11346335

    CAS  PubMed  Google Scholar 

  13. PE North M Waner A Mizeracki et al. (2001) ArticleTitleA unique microvascular phenotype shared by juvenile hemangiomas and human placenta Arch Dermatol 137 559–570 Occurrence Handle1:STN:280:DC%2BD3MzhsVKjtA%3D%3D Occurrence Handle11346333

    CAS  PubMed  Google Scholar 

  14. DE Clark SK Smith Y He et al. (1998) ArticleTitleA vascular endothelial growth factor antagonist is produced by the human placenta and released into the maternal circulation Biol Reprod 59 1540–1548 Occurrence Handle1:CAS:528:DyaK1cXnvVOgs7k%3D Occurrence Handle9828203

    CAS  PubMed  Google Scholar 

  15. PE North M Waner MC Brodsky (2002) ArticleTitleAre infantile hemangiomas of placental origin Ophthalmology 109 223–224 Occurrence Handle10.1016/S0161-6420(01)00994-0 Occurrence Handle11825799

    Article  PubMed  Google Scholar 

  16. OS Reshetnikova GJ Burton AP Milovanov EI Fokin (1996) ArticleTitleIncreased incidence of placental chorioangioma in high-altitude pregnancies: hypobaric hypoxia as a possible etiologic factor Am J Obstet Gynecol 174 557–561 Occurrence Handle1:STN:280:BymC1M7osFE%3D Occurrence Handle8623784

    CAS  PubMed  Google Scholar 

  17. CW Chang NA Rao JT Stout (1998) ArticleTitleHistopathology of the eye in diffuse neonatal hemangiomatosis Am J Ophthalmol 125 868–870 Occurrence Handle10.1016/S0002-9394(98)00049-X Occurrence Handle1:STN:280:DyaK1czgslKmug%3D%3D Occurrence Handle9645726

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Sevgi Bakaris.

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Bakaris, S., Karabiber, H., Yuksel, M. et al. Case of Large Placental Chorioangioma Associated with Diffuse Neonatal Hemangiomatosis. Pediatr. Dev. Pathol. 7, 258–261 (2004). https://doi.org/10.1007/s10024-003-4042-1

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  • DOI: https://doi.org/10.1007/s10024-003-4042-1

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