Abstract
Type II endoleaks after endovascular repair of abdominal aortic aneurysm (EVAR) are a result of retrograde flow from arterial branches (e.g., lumbar and inferior mesenteric) refilling the aneurysm sac, which has been excluded by the stent graft. Controversy continues with regard to the clinical significance and treatment of type II endoleaks. To develop recommendations for management, we analyzed outcome data from 10 EVAR trials completed over the last 5 years involving a total of 2,617 cases. The incidence of type II endoleak at discharge or 30 days was 6-17%, at 6 months 4.5-8%, and at 1 year 1-5%. Successful resolution of endoleak following secondary interventions was observed in 11-100% of cases. There were 10 conversions to open repair and no ruptures related to type II endoleak. In patients observed for 12 months with computed tomography and/or ultrasound, approximately one-half of type II endoleaks disappeared spontaneously. In the absence of a type I endoleak, our analysis of the current literature suggests that intervention for type II endoleak should be undertaken for abdominal aortic aneurysm sac enlargement occurring after 6 months, persistence for >12 months without abdominal aortic aneurysm sac enlargement, or an aneurysm sac pressure >20% of systolic blood pressure; translumbar aneurysm sac thrombosis and intra-arterial feeding vessel occlusion appear to be prudent management options.
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Parodi JC, Palmaz JC, Barone HD. Transfemoral intraluminal graft implantation for abdominal aortic aneurysms. Ann Vasc Surg 1991;5:491–9
Faries PL, Cadot H, Agarwal G, et al. Management of endoleak after endovascular aneurysm repair: cuffs, coils, and conversion. J Vasc Surg 2003;37:1155-1161
Parry DJ, Kessel DO, Robertson I, et al. Type II endoleaks: predictable, preventable, and sometimes treatable? J Vasc Surg 2002;36:105-110
Aquino RV, Rhee RY, Muluk SC, et al. Exclusion of accessory renal arteries during endovascular repair of abdominal aortic aneurysms. J Vasc Surg 2001;34:878-884
White GH. Type II endoleaks are not clinically significant: the case against. In: Greenhalgh R (ed), Vascular and Endovascular Controversies. London: Biba Publishing, 2003
Lee TJ, Aziz IN, Lee JT, et al. Volume regression of abdominal aortic aneurysms and its relation to successful endoluminal exclusion. J Vasc Surg 2003;38:1254-1263
Stavropulos SW, Clark TW, Carpenter JP et al. Use of CT angiography to classify endoleaks after endovascular repair of abdominal aortic aneurysms. J Vasc Interv Radiol 2005;16:663–7
Haulon S, Lions C, McFadden EP, et al. Prospective evaluation of magnetic resonance imaging after endovascular treatment of infrarenal aortic aneurysms. Eur J Vasc Endovasc Surg 2001;22:62-69
Parent FN, Meier GH, Godziachvili V, et al. The incidence and natural history of type I and II endoleaks: a 5-year follow-up assessment with color duplex ultrasound scan. J Vasc Surg 2002;35:474-481
d’Audiffret A, Desgranges P, Kobeiter DH, et al. Follow-up evaluation of endoluminally treated abdominal aortic aneurysms with duplex ultrasonography: validation with computed tomography. J Vasc Surg 2000;33:42-50.
Baum RA. Type II endoleaks after EVAR. Endovasc. Today 2003;43.
Veith FJ, Baum RA, Ohki T, et al. Nature and significance of endoleaks and endotension: summary of opinions expressed at an international conference. J Vasc Surg 2002;35:1029-1035
Hinchcliffe RJ, Singh-Ranger R, Davidson IR, et al. Rupture of an abdominal aortic aneurysm secondary to type II endoleak. Eur J Vasc Endovasc Surg 2001;22:663-665
Hans SS, Jareunpoon O, Huang R, et al. Relationship of residual intraluminal to intrathrombotic pressure in a closed aneurysmal sac. J Vasc Surg 2003;37:949–53
Sonesson B, Dias N, Malina M, et al. Intra-aneurysm pressure measurements in successfully excluded abdominal aortic aneurysm after endovascular repair. J Vasc Surg 2003;37:733-738
Baum RA, Carpenter JP, Cope C, et al. Aneurysm sac pressure measurements after endovascular repair of abdominal aortic aneurysms. J Vasc Surg 2001;33:32-41.
Harris PL, Vallahhaneni SR, Desgranges P, et al. Incidence and risk factors of late rupture, conversion, and death after endovascular repair of infrarenal aortic aneurysms: the EUROSTAR experience. European Collaboration on Stent/Graft Techniques for Aortic Aneurysm Repair. J Vasc Surg 2000;32:739-749
Bockler D, Probst T, Weber H, Raithel D. Surgical conversion after endovascular grafting for abdominal aortic aneurysm. J Endovasc Ther 2002;9:111-118
Haulon S, Tyazi A, Willoteaux S, et al. Embolization of type II endoleaks after aortic stent-graft implantation: technique and immediate results. J Vasc Surg 2001;34:600-605
Kasirajan K, Matteson, Marek, et al. Technique and results of transfemoral superselective coil embolization of type II lumbar endoleak. J Vasc Surg 2003;38:61-66.
Baum RA, Carpenter JP, Golden MA, et al. Treatment of type 2 endoleaks after endovascular repair of abdominal aortic aneurysms: comparison of transarterial and translumbar techniques. J Vasc Surg 2002;35:23-29
Liewald F, Ermis C, Gorich J, et al. Influence of treatment of type II leaks on the aneurysm surface area. Eur J Vasc Endovasc Surg 2001;21:339-343
Schmid R, Gurke L, Aschwanden M, Stierli P, Jacob AL. CT-guided percutaneous embolization of a lumbar artery maintaining a type II endoleak. J Endovasc Ther 2002;9:198-202
Baum RA, Cope C, Fairman RM, Carpenter JP. Translumbar embolization of type 2 endoleaks after endovascular repair of abdominal aortic aneurysms. J Vasc Interv Radiol 2001;12:111-116
Ilessel SJ, Adams DF, Abrams HL. Complications of angiography. Radiology 1981;138:273-281
Wisselink W, Cuesta MA, Berends FJ, et al. Retroperitoneal endoscopic ligation of lumbar and inferior mesenteric arteries as a treatment of persistent endoleak after endoluminal aortic aneurysm repair. J Vasc Surg 2000;31:1240-1244
Gould DA, McWilliams R, Edwards RD, et al. Aortic side branch embolization before endovascular aneurysm repair: incidence of type I endoleak. J Vasc Interv Radiol 2001;12:337-351
Walker SR, Macierewiez J, Hopkinson BR. Endovascular AAA repair: prevention of side branch endoleaks with thrombogenic sponge. J Endovasc Surg 1999;6:350-353.
Bush RL, Lin PH, Ronson KS, et al. Colonic necrosis subsequent to catheter directed thrombin embolization of the inferior mesenteric artery via the superior mesenteric artery: a complication in the management of type II endoleak. J Vasc Surg 2001;34:1119-1122
Miller FJ, Mineau DE. Transcatheter arterial embolization - major complications and their prevention. Cardiovasc Intervent Radiol 1983;6:141-149
Forester ND, Parry D, Kessel D, Robertson I, Patel J, Scott DJ. Ischemic sciatic neuropathy: an important complication of embolization of a type II endoleak. Eur J Vasc Endovasc Surg 2002;24:462-463
Chuter TA, Faruqi RM, Sahney R, et al. Endoleak after endovascular repair of abdominal aortic aneurysm. J Vasc Surg 2001;34:98-105
Solis MM, Ayerdi J, Babcock GA, et al. Mechanism of failure in the treatment of type II endoleak with percutaneous coil embolization. J Vasc Surg 2002;36:485-491
Sampram ESK, Karafa MT, Mascha EJ, et al. Nature, frequency, and predictors of secondary procedures after endovascular repair of abdominal aortic aneurysm. J Vasc Surg 2003;37:930-937
Farner MC, Carpenter J, Baum RA, Fairman RM. Early changes in abdominal aortic aneurysm diameter after endovascular repair. J Vasc Interv Radiol 2003;14:205-210
Zarins CK, White RA, Hodgson KJ, Shwarten D, Fogarty TJ. Endoleak as predictor of outcome after endovascular aneurysm repair: AneuRx multicenter clinical trial. J Vasc Surg 2000;32:90-107
Zarins CK, Bloch DA, Crabtree T, Matsumoto AH, White RA, Fogarty TJ. Aneurysm enlargement following endovascular aneurysm repair: AneuRx clinical trial. J Vasc Surg 2004;39:109-117
Carpenter JP, Anderson WN, Brewster DC, et al. Multicenter pivotal trial results of the Lifepath System for endovascular aortic aneurysm repair. J Vasc Surg 2004;39:34-42
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Gelfand, D.V., White, G.H. & Wilson, S.E. Clinical Significance of Type II Endoleak after Endovascular Repair of Abdominal Aortic Aneurysm. Ann Vasc Surg 20, 69–74 (2006). https://doi.org/10.1007/s10016-005-9382-z
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DOI: https://doi.org/10.1007/s10016-005-9382-z